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Paraphaeosphaeria sporulosa

ABSTRACT: Soil-borne fungus

PROVIDER: PRJNA259257 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR11823732_1.fastq.gz	Fastqsanger.gz
	SRR11823732_2.fastq.gz	Fastqsanger.gz
	SRR4063290_1.fastq.gz	Fastqsanger.gz
	SRR4063290_2.fastq.gz	Fastqsanger.gz

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Antibiotic Activity of a Paraphaeosphaeria sporulosa-Produced Diketopiperazine against Salmonella enterica.

Project description:A diketopiperazine has been purified from a culture filtrate of the endophytic fungus Paraphaeosphaeria sporulosa, isolated from healthy tissues of strawberry plants in a survey of microbes as sources of anti-bacterial metabolites. Its structure has been determined by nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LC-MS) analyses and was found to be identical to cyclo(L-Pro-L-Phe) purified from species of other fungal genera. This secondary metabolite has been selected following bioguided-assay fractionation against two strains of Salmonella enterica, the causal agent of bovine gastroenteritis. The diketopiperazine cyclo(L-Pro-L-Phe), isolated for the first time from Paraphaeosphaeria species, showed minimum inhibitory concentration (MIC) values of 71.3 and 78.6 μg/mL against the two S.enterica strains. This finding may be significant in limiting the use of synthetic antibiotics in animal husbandry and reducing the emergence of bacterial multidrug resistance. Further in vivo experiments of P. sporulosa diketopiperazines are important for the future application of these metabolites.

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Paraphaeosphaeria sporulosa strain:DISAAA10515

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Project description:Paraphaeosphaeria sporulosa strain:AP3s5-JAC2a Transcriptome or Gene expression

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Genome-wide profiling of Arabidopsis thaliana Col-0 and ein2/jar1 host responses to Macrophomina phaseolina infection

Project description:Macrophomina phaseolina (Mp) is a soil-borne pathogenic fungus known to infect more than 500 plants species including important crops. Here we report the use of a novel agar plate-based pathosystem using the model plant Arabidopsis thaliana (Arabidopsis) to study plant defense reponses to Mp, specifically a comparison between wild type Col-0 and double mutant ein2/jar1 roots with and without Mp infection, at two time points, by RNA-seq.

2020-01-08 | GSE127574 | GEO

The transcriptional landscape of Nicotiana benthamiana and Verticillium dahliae interaction

Project description:Verticillium dahliae is a soil-borne fungus with a broad host range, including the model plants Nicotiana benthamiana and Arabidopsis thaliana. The plant immunity can be activated by Vd-derived patterns while V. dahliae secreted effectors. We report here the RNAseq analyses of samples from N. benthamiana infected by V. dahliae strains 592 and 171 at different time points. The data showed dynamic expression patterns of genes not only from plant defense signaling but also plant developmental signaling.

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2022-03-02 | GSE190467 | GEO

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