Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Plasmodium falciparum strain:W2

ABSTRACT: Plasmodium falciparum Genome sequencing of MMV008138 resistant strains

PROVIDER: PRJNA268972 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR1686810.fastq.gz	Fastqsanger.gz
	SRR1686811.fastq.gz	Fastqsanger.gz
	SRR1686812.fastq.gz	Fastqsanger.gz
	SRR1686813.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Plasmodium falciparum strain:W2

Project description:Plasmodium falciparum SJ25081 resistant mutant Genome sequencing

| PRJNA338989 | ENA

Plasmodium falciparum strain:W2

Project description:Plasmodium falciparum strain:W2 Genome sequencing

| PRJNA251650 | ENA

Plasmodium falciparum

Project description:Plasmodium falciparum genome sequencing of imidazolopiperazine resistant strains

| PRJNA82741 | ENA

Plasmodium falciparum W2/Dd2 Day 8 gametocytes

Project description:The sexual stages are vital phases in malaria parasite transmission and are the targets of various interventions such as transmission blocking vaccines. The molecular mechanisms underlying sexual development, however, remain poorly understood. We report mappping of a determinant previously linked to a male gametocyte development defect in the P. falciparum Dd2 parasite to an 82 kb region on chromosome 12. In order to find a critical gene in this region, we compared gene expression pattern in sexual stage of the parasite between Dd2 and its normal gametocyte-producing ancestor W2 clones. The region contains a sexual stage specific gene (pfmdv 1) that is expressed substantially at a lower level in the Dd2 than in W2 parasite. Disruption of pfmdv 1 results in a dramatic reduction in mature gametocytes, especially male gametocytes, with the majority of sexually committed parasites arrested at stage-I. The pfmdv-1 knockout parasites show an enlarged nucleus, often with separation of the inner and outer nuclear membranes and presence of multi-membrane vesicles in red blood cell cytoplasm. Mosquito infectivity of the knockout parasites is also greatly reduced, but not completely lost, suggesting presence of compensatory mechanisms in the sexual development pathways. Data include Day 8 gametocytes of male defective Dd2 and parental W2 clones of Plasmodium falciparum. The series includes three biological repeats. Keywords: repeat sample

2005-05-01 | GSE2265 | GEO

Plasmodium falciparum

Project description:Genome Sequencing of Plasmodium falciparum Malawi strains

| PRJNA187991 | ENA

Plasmodium falciparum

Project description:Hesparadin-resistant Plasmodium falciparum

| PRJNA597922 | ENA

Plasmodium falciparum W2/Dd2 Day 8 gametocytes

2010-06-10 | E-GEOD-2265 | biostudies-arrayexpress

Plasmodium falciparum

Project description:Comparative genome sequencing project of Plasmodium falciparum strains

| PRJNA27925 | ENA