Project description:Primary objectives: The primary objective is to investigate circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS). Primary endpoints: circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).

| 2533916 | ecrin-mdr-crc

Malaciobacter marinus strain:UTICA-S4D1

Project description:Arcobacter marinus UTICA-S4D1 Genome sequencing

| PRJNA370004 | ENA

Malaciobacter marinus strain:SH-4D_Col1

Project description:Arcobacter marinus SH-4D_Col1 genome sequencing

| PRJNA367813 | ENA