Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Expression data from control, aged and activated neutrophils in mouse blood

OTHER RELATED OMICS DATASETS IN: E-GEOD-69886

PROVIDER: PRJNA287025 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

E-GEOD-69886

Project description:Expression data from control, aged and activated neutrophils in mouse blood

2016-01-08 | E-GEOD-69886 | ExpressionAtlas

E-GEOD-42230

Project description:Expression data from P15 mouse testes control and Ikbkap-knockout mice

2015-07-08 | E-GEOD-42230 | ExpressionAtlas

Expression data from control, aged and activated neutrophils in mouse blood

Project description:Neutrophils provide immune protection against pathogens but also may promote tissue injury in inflammatory diseases. Although neutrophils are generally considered as a relatively homogeneous population, evidence for heterogeneity is emerging. Under steady-state conditions, neutrophil heterogeneity may arise from ageing and the replenishment by newly released neutrophils from the bone marrow. We used microarray to globally analyze gene expression in aged neutrophils and characterize the inflammatory programs that are activated during the aging process in the circulation. Control, aged and activated neutrophils were sorted directly from mouse blood for RNA extraction and hybridization on Affymetrix microarrays. We transfused whole blood and harvested donor neutrophils marked by the CD45.1 allele 6h later to derive neutrophils that had truly aged in vivo. Sorted neutrophils were compared to control donor neutrophils that had been transferred for only 10 min. Additionally, we harvested circulating neutrophils from TNF-? treated mice for comparison with neutrophils activated by systemic inflammation.

2015-09-24 | E-GEOD-69886 | biostudies-arrayexpress

E-GEOD-45826

Project description:Expression data from sorted control and Pygo2-null mouse mammary stem/basal cells

2015-07-13 | E-GEOD-45826 | ExpressionAtlas

E-GEOD-54992

Project description:Expression data from peripheral blood

2025-01-24 | E-GEOD-54992 | ExpressionAtlas

Testis expression in Mus musculus domesticus x Mus musculus musculus hybrid zone mice

Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility. Gene expression was measured in whole testis from males aged 62-86 days. Samples include 190 first generation lab-bred male offspring of wild-caught mice from the Mus musculus musculus - M. m. domesticus hybrid zone.

2014-12-04 | E-GEOD-61417 | biostudies-arrayexpress

E-GEOD-17157

Project description:Expression data from E18.5 Igf1 -/- (homozygous mutant) and Igf1+/+ (normal wild type control) mouse lungs

2015-07-07 | E-GEOD-17157 | ExpressionAtlas

E-GEOD-39009

Project description:Expression data from mouse skeletal muscle

2015-09-29 | E-GEOD-39009 | ExpressionAtlas

E-GEOD-53403

Project description:Expression data from mouse adipose tissue macrophage

2015-07-31 | E-GEOD-53403 | ExpressionAtlas

E-GEOD-35961

Project description:Expression data from mouse liver treated with metformin