Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Conversion of Fibroblasts into Functional Trophoblast Stem-like Cells

PROVIDER: PRJNA288028 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR2077080.fastq.gz	Fastqsanger.gz
	SRR2077081.fastq.gz	Fastqsanger.gz
	SRR2077082.fastq.gz	Fastqsanger.gz
	SRR2077083.fastq.gz	Fastqsanger.gz
	SRR2077084.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 9

Similar Datasets

Mus musculus

Project description:Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells

| PRJNA271620 | ENA

Mus musculus

Project description:Direct Conversion of Trophoblast Stem Cells into Pluripotent Stem Cells by Oct4

| PRJNA134681 | ENA

Mus musculus

Project description:Conversion of murine extraembryonic trophoblast stem cells into induced pluripotent stem cells

| PRJNA135799 | ENA

Conversion of Fibroblasts into Functional Trophoblast Stem-like Cells

Project description:Here we demonstrate the generation of stable induced trophoblast stem cells (iTSCs) from fibroblasts by the transient expression of Gata3, Eomes and Tfap2c. Transcriptome and methylome analyses and functional assays such as hemorrhagic lesion formation and placenta contribution suggested a high degree of conversion. Careful examination of the reprogramming process indicated that the cells did not go through a transient pluripotent state. Detect and compare different H2A.X deposition patterns in ES cells,MEFs and iTSC and TS cells, with Illumina HiSeq 2000

2016-07-05 | E-GEOD-70234 | biostudies-arrayexpress

Mus musculus

Project description:Trophoblast stem cells

| PRJNA93945 | ENA

Mus musculus

Project description:Direct conversion of fibroblasts into stably expandable neural stem cells

| PRJNA158995 | ENA

Conversion of Fibroblasts into Functional Trophoblast Stem-like Cells

2016-01-03 | GSE70234 | GEO

Mus musculus

Project description:Transcriptome of Trophoblast Stem Cells

| PRJNA380814 | ENA

Mus musculus

Project description:Breaking the lineage barrier: Direct induction of trophoblast stem cells from murine fibroblasts

| PRJNA270765 | ENA

Bidirectional Introgression between Mus musculus domesticus and Mus spretus.

Project description:Introgressed variants from other species can be an important source of genetic variation because they may arise rapidly, can include multiple mutations on a single haplotype, and have often been pretested by selection in the species of origin. Although introgressed alleles are generally deleterious, several studies have reported introgression as the source of adaptive alleles-including the rodenticide-resistant variant of Vkorc1 that introgressed from Mus spretus into European populations of Mus musculus domesticus. Here, we conducted bidirectional genome scans to characterize introgressed regions into one wild population of M. spretus from Spain and three wild populations of M. m. domesticus from France, Germany, and Iran. Despite the fact that these species show considerable intrinsic postzygotic reproductive isolation, introgression was observed in all individuals, including in the M. musculus reference genome (GRCm38). Mus spretus individuals had a greater proportion of introgression compared with M. m. domesticus, and within M. m. domesticus, the proportion of introgression decreased with geographic distance from the area of sympatry. Introgression was observed on all autosomes for both species, but not on the X-chromosome in M. m. domesticus, consistent with known X-linked hybrid sterility and inviability genes that have been mapped to the M. spretus X-chromosome. Tract lengths were generally short with a few outliers of up to 2.7 Mb. Interestingly, the longest introgressed tracts were in olfactory receptor regions, and introgressed tracts were significantly enriched for olfactory receptor genes in both species, suggesting that introgression may be a source of functional novelty even between species with high barriers to gene flow.

| S-EPMC8784167 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data