Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bos taurus

ABSTRACT: The repressive regulatory role of H3K27me3 histone mark in bovine mastitis resistance to Staphylococcus aureus

PROVIDER: PRJNA290927 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR2126920.fastq.gz	Fastqsanger.gz
	SRR2126921.fastq.gz	Fastqsanger.gz
	SRR2126922.fastq.gz	Fastqsanger.gz
	SRR2126917.fastq.gz	Fastqsanger.gz
	SRR2126918.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

LncRNA-sequencing of bovine MAC-T cells

Project description:Escherichia coli and Staphylococcus aureus are two common pathogenic microorganisms that cause mastitis in dairy cows. They can cause clinical mastitis and subclinical mastitis. In recent studies, lncRNAs have been found to play an important role in the immune responses triggered by microbial inducers. However, the actions of lncRNAs in bovine mastitis remain unclear. The purpose of this study was to explore the lncRNA profile on mastitis.

2021-08-06 | GSE181464 | GEO

Norwegian Red (NRF) cattle macrophage challenge1

Project description:In vitro challenge of bovine macrophages (derived from blood monocytes)with live bacteria of a Staphylococcus aureus strain isolated from a clinical mastitis case.

2012-01-01 | E-TABM-1133 | biostudies-arrayexpress

Transcriptome profiling of m6A mRNA modification in inflammation of bovine mammary epithelial cells infected by Staphylococcus aureus and Escherichia coli

Project description:Mastitis is a common disease in dairy cows and brings massive losses to the dairy industry. m6A is a type of modification strongly associated with many diseases. However, the role of m6A in mastitis caused by Staphylococcus aureus and Escherichia coli has not been investigated.We used MeRIP-seq technology to sequence the bovine mammary epithelial cells (MAC-T) infected with inactivated S. aureus/E. coli for 24 h.

2020-11-09 | GSE161050 | GEO

Transcription profiling of Bos taurus mammary gland infected with E. coli or S. aureus to investigate response to pathogen invasion and identify general and pathogen-specific transcriptional profiles

Project description:Investigation of the bovine mammary gland response to Escherichia coli and Staphylococcus aureus infection. The aims of the study were to examine the dynamics of the mammary gland response to pathogen invasion and identify general and pathogen-specific transcriptional profiles. Individual udder quarters of 12 cows were sequentially inoculated with either E. coli or S. aureus over 24 or 72 hours before culling, whilst one quarter was used as an uninfected control.

2011-05-01 | E-TABM-704 | biostudies-arrayexpress

Comparative Expression Profiling of E. coli and S. aureus inoculated primary Mammary Gland Cells sampled from Cows with different genetic Predisposition for Somatic Cell Score

Project description:Establishment of an in vitro system to explore molecular mechanisms of mastitis susceptibility in cattle by comparative expression profiling of Escherichia coli and Staphylococcus aureus inoculated primary cells sampled from cows with different genetic predisposition for somatic cell score Primary bovine mammary gland epithelial cells (pbMEC) were sampled from the udder parenchyma of cows that were selected for high and low mastitis susceptibility by applying a marker assisted selection strategy considering QTL and molecular marker information of a repetitively confirmed QTL for SCS in the telomeric region on BTA18 The cells were cultivated and subsequently inoculated with heat inactivated mastitis pathogens Escherichia coli and Staphylococcus aureus, respectively. After 1, 6 and 24 hours the cells were harvested and comparatively analyzed using microarray expression chip technology to identify differences in mRNA expression profiles attributed to cultivation, inoculation or to genetic predisposition.

2011-07-27 | GSE24560 | GEO

Bos taurus

Project description:Response of bovine mammary tissue to experimental Staphylococcus aureus infection experiment 3.

| PRJNA105091 | ENA

Bos taurus

Project description:Response of bovine mammary tissue to experimental Staphylococcus aureus infection experiment 2.

| PRJNA105089 | ENA

Bos taurus

Project description:Response of bovine mammary tissue to experimental Staphylococcus aureus infection experiment 1.

| PRJNA105199 | ENA

Response of bovine mammary tissue to experimental Staphylococcus aureus infection experiment 2.

Project description:Mastitis in dairy cattle can result from infection by a range of microorganisms but is principally caused by coliform bacteria and gram positive bacteria such as Staphylococcus aureus (S. aureus). The former species are often acquired by environmental contamination while S. aureus is particularly problematic due to its resistance to antibiotic treatments and ability to reside within mammary tissue in a chronic, subclinical state. The transcriptional and translational responses within bovine mammary epithelial tissue subjected to intramammary challenge with S. aureus are poorly characterised, particularly at the earliest stages of infection. A Bovine Innate Immune Microarray was employed to measure changes in gene expression occurring in bovine mammary tissues sampled from three dairy cows after a brief and graded intramammary challenge with a virulent strain of S. aureus. Keywords: dose response, disease state analysis

2010-05-20 | GSE9680 | GEO

Response of bovine mammary tissue to experimental Staphylococcus aureus infection experiment 1.

2010-05-20 | GSE9628 | GEO