Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Investigation of the molecular mechanism of liver regeneration by the multi-omics approach (ChIP-seq)

PROVIDER: PRJNA296363 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR2452510_1.fastq.gz	Fastqsanger.gz
	SRR2452510_2.fastq.gz	Fastqsanger.gz
	SRR2452520_1.fastq.gz	Fastqsanger.gz
	SRR2452520_2.fastq.gz	Fastqsanger.gz
	SRR2452511_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 40

Similar Datasets

Mus musculus

Project description:Investigation of the molecular mechanism of liver regeneration by the multi-omics approach

| PRJNA295999 | ENA

ALDOC- and ENO2- driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis

Project description:Investigation of lung adenocarcinoma (LUAD) and breast cancer cells cultured in either a nutrient-rich or -restricted culture conditions trough a multi-omics approach, including transcriptomics, to explore the molecular changes underlying the transition from 2D to 3D cultures.

2023-04-05 | GSE215235 | GEO

A hyper-quiescent chromatin state formed during aging is reversed by regeneration

Project description:Epigenetic alterations are a key hallmark of aging but have not been extensively explored in tissues. Here, using naturally aged murine liver as a model and extending study to other quiescent tissues, we find that aging is driven by temporal chromatin alterations that promote a refractory cellular state and compromise cellular identity. Using an integrated multi-omics approach and the first direct visualization of aged chromatin, we find that old cells show global H3K27me3-driven broad heterochromatinization and transcription suppression. At the local level, site-specific loss of H3K27me3 from promoters of genes encoding developmental transcription factors leads to expression in liver of non-hepatocyte markers. Interestingly, liver regeneration reverses H3K27me3 patterns and rejuvenates multiple molecular and physiological aspects of the aged liver.

2023-03-17 | GSE223480 | GEO

A hyper-quiescent chromatin state formed during aging is reversed by regeneration [ChIP-seq]

2023-03-17 | GSE185704 | GEO

Mus musculus

Project description:Integrated multi-omics Landscape of liver metastases

| PRJNA831718 | ENA

Mus musculus

Project description:Multi-omics analysis of the biological mechanism of the pathogenesis of non-alcoholic fatty liver disease

| PRJNA1068522 | ENA

Integrative multi-omics approach for mechanism of humidifier disinfectant-associated lung injury

Project description:Integrative multi-omics approach for mechanism of humidifier disinfectant-associated lung injury

| PRJNA743863 | ENA

Multi-omics approaches for liver reveal the antithrombotic mechanism of aspirin eugenol ester in rat thrombosis model

Project description:This study aimed to investigate the effect of AEE on the liver of thrombosed rats to reveal its mechanism of thromboprophylaxis. Therefore, a multi-omics approach was used to analyze the liver.

2024-02-02 | PXD049461 |

Mus musculus

Project description:Prediction of gene activity based on an integrated multi-omics approach.

| PRJNA228967 | ENA

Molecular characterization of the intact muscle spindle using a multi-omics approach

Project description:Molecular characterization of the intact muscle spindle using a multi-omics approach

| PRJNA858470 | ENA