Project description:WhiB4 regulates expression of anti-oxidant genes and survival of Mtb in resposne to oxidaitve stress. Thus, we did microarray upon exposure to 0.25 mM CHP for Wt Mtb and MtbΔwhiB4 strain complemented with whiB4 gene to study the restoration of gene expression to wild type levels.
Project description:Transcriptional profiling of M.tuberculosis to 10 mM vitamin C at 0.25, 0.5, 1, 2 , 4, 8 and 24 h compared to gene expression profile of untreated M. tuberculosis culture (0 h).
Project description:To understand the response of M. tuberculosis (MTB) to the drug BTZ043, we performed transcriptomics on MTB bacilli exposed to the drug.
Project description:To understand the response of M. tuberculosis (MTB) to the drug sulfamethoxazole, we performed transcriptomics on MTB bacilli exposed to the drug.
Project description:To understand the response of M. tuberculosis (MTB) to the drug delamanid, we performed transcriptomics on MTB bacilli exposed to the drug.
Project description:To understand the response of M. tuberculosis (MTB) to the drug sutezolid, we performed transcriptomics on MTB bacilli exposed to the drug.
Project description:To understand the response of M. tuberculosis (MTB) to the drug SQ109, we performed transcriptomics on MTB bacilli exposed to the drug.
Project description:To understand the response of M. tuberculosis (MTB) to the drug linezolid, we performed transcriptomics on MTB bacilli exposed to the drug.
