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Yersinia pestis biovar Orientalis str. India 195

ABSTRACT: Strain from India

PROVIDER: PRJNA30507 | ENA |

REPOSITORIES: ENA

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Yersinia pestis biovar Orientalis str. PEXU2

Project description:Biovar Orientalis strain for comparative analysis

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Conserved filamentous prophage in Escherichia coli O18:K1:H7 and Yersinia pestis biovar orientalis.

Project description:Microbial virulence is known to emerge by horizontal gene transfer mechanisms. Here we describe the discovery of a novel filamentous prophage, designated CUS-1, which is integrated into the chromosomal dif homologue of the high-virulence clone Escherichia coli O18:K1:H7. An homologous chromosomal element (CUS-2) in Yersinia pestis biovar orientalis is integrated at the same relative location as CUS-1; both lysogenic E. coli and Y. pestis strains produce particles with properties expected of single-stranded DNA virions. CUS(phi) is epidemiologically correlated with the emergence of K1 strains with increased virulence and with the Y. pestis biovar responsible for the current (third) plague pandemic.

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Yersinia pestis biovar Orientalis str. BA200901703