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DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at EDIC years 16/17 yrs from participants of DCCT/EDIC study

ABSTRACT: DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at EDIC years 16/17 yrs from participants of DCCT/EDIC study

PROVIDER: PRJNA306514 | ENA |

REPOSITORIES: ENA

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DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at EDIC years 16/17 yrs from participants of DCCT/EDIC study

Project description:DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at EDIC years 16/17 years from participants of Diabetes Control and Complications Trial/ Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study This SuperSeries is composed of the SubSeries listed below.

2016-05-15 | GSE76171 | GEO

DNA-methylation profiling of Whole blood genomic DNAs collected at EDIC baseline and monocytes at EDIC years 16/17 yrs from participants of DCCT/EDIC study

2016-05-15 | E-GEOD-76171 | biostudies-arrayexpress

DNA-methylation profiling of monocyte genomic DNAs collected from participants of Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study

2016-05-15 | GSE76170 | GEO

DNA-methylation profiling of Whole blood genomic DNAs collected from participants of Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study

2016-05-15 | GSE76169 | GEO

Project description:Study the association of DNA-methylation and metabolic memory by examing DNA-methylation alternation between cases (received conventional therapy in DCCT and showing retinopathy or albuminuria progression at EDIC year-10) and Controls (in DCCT intensive treatment group and did not have retinopathy or nephropathy progression during EDIC). Bisulphite converted DNA from the 63 whole blood samples (32 Cases and 31 Controls) were hybridised to the Illumina Infinium HumanMethylation450 Beadchip arrays.

2016-05-15 | E-GEOD-76169 | biostudies-arrayexpress

DNA-methylation profiling of monocyte genomic DNAs collected from participants of Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study

Project description:Study the association of DNA-methylation and metabolic memory by examing DNA-methylation alternation between cases (received conventional therapy in DCCT and showing retinopathy or albuminuria progression at EDIC year-10) and Controls(in DCCT intensive treatment group and did not have retinopathy or nephropathy progression during EDIC] Bisulphite converted DNA from the 61 monocyte samples (31 Cases and 30 Controls) were hybridised to the Illumina Infinium HumanMethylation450 Beadchip arrays. Please note that the same samples were used on histone-modification profilling in PMID:24458354

2016-05-15 | E-GEOD-76170 | biostudies-arrayexpress

ChIP-chip Monocyte H3K9Ac from DCCT/EDIC patients

Project description:Chromatin immunoprecipitation linked to tiling arrays (ChIP-chip) were performed to profile histone H3K9Ac at 22K gene promoters in peripheral blood monocytes obtained in 2009-10 from 60 selected DCCT participants being followed in the long-term observational EDIC study.

2013-12-31 | GSE47384 | GEO

ChIP-chip Monocyte H3K4Me3 from DCCT/EDIC patients

Project description:Chromatin immunoprecipitation linked to tiling arrays (ChIP-chip) were performed to profile histone H3K4Me3 at 22K gene promoters in peripheral blood monocytes obtained in 2009-10 from 60 selected DCCT participants being followed in the long-term observational EDIC study.

2013-12-31 | GSE47383 | GEO

ChIP-chip Lymphocyte H3K9Me2 from DCCT/EDIC patients

Project description:Chromatin immunoprecipitation linked to tiling arrays (ChIP-chip) were performed to profile histone H3K9Me2 at 22K gene promoters in peripheral blood lymphocytes obtained in 2009-10 from 60 selected DCCT participants being followed in the long-term observational EDIC study.

2013-12-31 | GSE47382 | GEO

ChIP-chip Lymphocyte H3K9Ac from DCCT/EDIC patients

Project description:Chromatin immunoprecipitation linked to tiling arrays (ChIP-chip) were performed to profile histone H3K9Ac at 22K gene promoters in peripheral blood lymphocytes obtained in 2009-10 from 60 selected DCCT participants being followed in the long-term observational EDIC study.

2013-12-31 | GSE47381 | GEO

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