Cochliomyia hominivorax strain:Panama 95
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA30971 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:The New World screw-worm fly is a parasitic fly whose larvae eat the living tissue of warm-blooded animals
| PRJNA30975 | ENA
Project description:Deep sequencing of New World screw-worm transcripts to discover genes involved in insecticide resistance
| PRJNA79705 | ENA
Project description:New World Screwworm Fly (Cochliomyia hominivorax) Genome Assembly and Developmental Gene Expression Analyses
| PRJNA641284 | ENA
Project description:Identification and Characterization of MicroRNAs from the New World Screwworm Fly Cochliomyia hominivorax (Diptera: Calliphoridae)
| PRJNA274978 | ENA
Project description:The testes transcriptome derived from the New World Screwworm, Cochliomyia hominivorax
| PRJNA324578 | ENA
Project description:454 sequencing of Cochliomyia hominivorax transcriptome
| PRJNA79389 | ENA
Project description:Cochliomyia hominivorax Transcriptome or Gene expression
| PRJNA254379 | ENA
Project description:Cochliomyia hominivorax Raw sequence reads
| PRJNA414339 | ENA
Project description:Myasis is the infestation by fly larvae (Diptera) in live vertebrates including humans. Myasis has been reported most commonly in tropical and subtropical areas around the world with poor sanitation and presence of cattle. Neonatal umbilical myiasis is an important cause of death in bovines and produces major economic losses in the livestock industry. However, its presentation in humans is rare, with a few cases reported worldwide. Moreover, umbilical myasis can be life-treating due to the risk of larvae migration to deeper tissues of the abdomen, omphalitis, and sepsis. We describe the case of a 7-day-old infant admitted to the hospital due to umbilical cord myiasis. In total, 55 larvae were removed from the wound and identified as Cochliomyia hominivorax. The patient recovered satisfactorily after treatment with ivermectin and amoxicillin. A literature search was performed in Pubmed, Medline, Lilacs and Google Scholar, with 64 cases of myasis by C. hominivorax being reviewed. Oral cavity, wounds, scalp and natural orifices are the main affected anatomical areas. Risk factors include the extremes of age, male sex, poor hygiene, alcohol and drug use, cancer, and mental disability. Programs for human myiasis prevention and surveillance are needed in neotropical areas where living conditions make it difficult to implement control strategies.
| S-EPMC6987426 | biostudies-literature
Project description:Transformer (TRA) promotes female development in several dipteran species including the Australian sheep blowfly Lucilia cuprina, the Mediterranean fruit fly, housefly and Drosophila melanogaster. tra transcripts are sex-specifically spliced such that only the female form encodes full length functional protein. The presence of six predicted TRA/TRA2 binding sites in the sex-specific female intron of the L. cuprina gene suggested that tra splicing is auto-regulated as in medfly and housefly. With the aim of identifying conserved motifs that may play a role in tra sex-specific splicing, here we have isolated and characterized the tra gene from three additional blowfly species, L. sericata, Cochliomyia hominivorax and C. macellaria. The blowfly adult male and female transcripts differ in the choice of splice donor site in the first intron, with males using a site downstream of the site used in females. The tra genes all contain a single TRA/TRA2 site in the male exon and a cluster of four to five sites in the male intron. However, overall the sex-specific intron sequences are poorly conserved in closely related blowflies. The most conserved regions are around the exon/intron junctions, the 3' end of the intron and near the cluster of TRA/TRA2 sites. We propose a model for sex specific regulation of tra splicing that incorporates the conserved features identified in this study. In L. sericata embryos, the male tra transcript was first detected at around the time of cellular blastoderm formation. RNAi experiments showed that tra is required for female development in L. sericata and C. macellaria. The isolation of the tra gene from the New World screwworm fly C. hominivorax, a major livestock pest, will facilitate the development of a "male-only" strain for genetic control programs.
| S-EPMC3567074 | biostudies-literature