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Lichtheimia ramosa

ABSTRACT: A causative organism of mucormycosis

PROVIDER: PRJNA318415 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	ERR501402.fastq.gz	Fastqsanger.gz
	ERR501403.fastq.gz	Fastqsanger.gz
	ERR501404.fastq.gz	Fastqsanger.gz
	ERR502960_1.fastq.gz	Fastqsanger.gz

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Lichtheimia ramosa B5792

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Lichtheimia ramosa B5399

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Complete Mitochondrial Genome Sequence of Lichtheimia ramosa (syn. Lichtheimia hongkongensis).

Project description:We report the complete mitochondrial genome sequence of Lichtheimia ramosa (syn. Lichtheimia hongkongensis), the first complete mitochondrial DNA sequence of the genus Lichtheimia. This 31.8-kb mitochondrial genome encodes 11 subunits of respiratory chain complexes, 3 ATP synthase subunits, 25 tRNAs, and small and large rRNAs, with the gene order atp9-cox2-atp6-cox3-cox1-nad2-nad3-cob-nad1-nad6-nad5-nad4l-nad4-atp8.

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Striatal necrosis caused by Lichtheimia ramosa in a neonatal calf.

Project description:A 12-day-old male calf that did not want breast milk from birth died following neurological signs such as staggering. Postmortem examination revealed bleeding and encephalomalacia in the left striatum and frontal lobe. Histopathologically, necrotic granulomatous encephalitis with numerous fungi was detected. The fungi were positively stained with anti-Rhizomucor mouse monoclonal antibodies. Lichtheimia ramosa was detected in formalin-fixed paraffin-embedded samples of the affected tissue by molecular methods. To the best of our knowledge, striatal necrosis caused by L. ramosa in a neonatal calf has not been reported. This study provides the first evidence of striatal necrosis caused by L. ramosa in a neonatal calf.

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Lichtheimia ramosa

Project description:Lichtheimia ramosa Genome sequencing

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De Novo Whole-Genome Sequence and Genome Annotation of Lichtheimia ramosa.

Project description:We report the annotated draft genome sequence of Lichtheimia ramosa (JMRC FSU:6197). It has been reported to be a causative organism of mucormycosis, a rare but rapidly progressive infection in immunocompromised humans. The functionally annotated genomic sequence consists of 74 scaffolds with a total number of 11,510 genes.

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Wound infection caused by Lichtheimia ramosa due to a car accident.

Project description:A 32-year-old immunocompetent man sustained severe traumas contaminated with organic material due to a car accident. An infection caused by Lichtheimia ramosa at the site of contamination was early diagnosed and cured by multiple surgical debridement and daily cleansing with antiseptic solution only.

| S-EPMC3885937 | biostudies-literature

A significant number of reported Absidia corymbifera (Lichtheimia corymbifera) infections are caused by Lichtheimia ramosa (syn. Lichtheimia hongkongensis): an emerging cause of mucormycosis.

Project description:Recently, we and others reported the discovery of Lichtheimia ramosa (syn. Lichtheimia hongkongensis). We also hypothesized that a proportion of 'Absidia corymbifera (Lichtheimia corymbifera)' reported in the literature could be L. ramosa. In this study, we characterized 13 strains that had been reported as 'A. corymbifera (L. corymbifera)' in the literature over an 11-year period. Microscopic examination of agar block smear preparations of all 13 strains showed abundant circinate side branches and pleomorphic giant cells with finger-like projections of L. ramosa. ITS1-5.8S-ITS2 rRNA gene cluster (internal transcribed spacer (ITS)) and partial elongation factor-1alpha (EF1α) gene sequencing showed that all 13 strains were clustered with L. ramosa; partial β-actin gene sequencing showed that most of the 13 strains were clustered with L. ramosa; and partial 28S rRNA gene sequencing showed that all 13 strains were clustered with L. ramosa, but one strain of L. corymbifera (HKU25) was also clustered with other strains of L. ramosa. A significant number of reported A. corymbifera (L. corymbifera) infections are L. ramosa infections which are of global distribution. In clinical microbiology laboratories, L. ramosa should be suspected if an Absidia-like mold that possesses abundant circinate side branches on the sporangiophores and pleomorphic giant cells with finger-like projections is observed. ITS and partial EF1α gene sequencing are more reliable than partial β-actin and 28S rRNA gene sequencing for identification of the Lichtheimia species.

| S-EPMC3630919 | biostudies-literature

WGS of Lichtheimia ramosa

Project description:Genome sequencing and annotation of Lichtheimia ramosa JMRC:FSU:6197

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Lichtheimia ramosa isolate:KPH11

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