Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Actinosynnema pretiosum strain:ATCC 31280

ABSTRACT: Actinosynnema pretiosum strain:ATCC 31280 Genome sequencing and assembly

PROVIDER: PRJNA323403 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Transcriptome of ansamitocin P-3 producer Actinosynnema pretiosum ATCC 31280

Project description:In submerged cultivation of filamentous microbes, including actinomycetes, complex morphology is one of the critical process features for secondary metabolites production. Ansamitocin P-3 (AP-3), an antitumor agent, is a secondary metabolite produced by Actinosynnema pretiosum ATCC 31280. An excessive mycelial fragmentation of A. pretiosum ATCC 31280 was observed during the early stage of fermentation. In order to identify genes involved in the early mycelial fragmentation, the total RNAs of mycelia collected at 15, 18, and 24 h were extracted and subjected to transcriptome sequencing using RNA-seq technology.Through comparative transcriptomic analysis, a subtilisin-like serine peptidase encoded gene APASM_4178 was identified to be responsible for the mycelial fragmentation. Mutant WYT-5 with the APASM_4178 deletion showed increased biomass and improved AP-3 yield by 43.65%.

2020-05-25 | GSE151010 | GEO

Actinosynnema pretiosum subsp. pretiosum strain:ATCC 31280

Project description:Actinosynnema pretiosum subsp. pretiosum strain:ATCC 31280 Genome sequencing

| PRJNA722727 | ENA

Actinosynnema pretiosum subsp. pretiosum strain:ATCC 31280

Project description:Actinosynnema pretiosum subsp. pretiosum strain:ATCC 31280 Genome sequencing and assembly

| PRJNA471980 | ENA

Actinosynnema pretiosum subsp. pretiosum strain:ATCC 31280

Project description:Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 ansamitocin gene cluster II

| PRJNA362988 | ENA

Actinosynnema pretiosum subsp. pretiosum strain:ATCC 31280

Project description:Actinosynnema pretiosum subsp. pretiosum strain ATCC 31280 ansamitocin gene cluster I

| PRJNA361200 | ENA

Transcriptome of the ansamitocin producer Actinosynnema pretiosum ATCC 31280

Project description:Transcriptome of the ansamitocin producer Actinosynnema pretiosum ATCC 31280

| PRJNA475541 | ENA

Transcriptome of ansamitocin P-3 producer Actinosynnema pretiosum ATCC 31280

Project description:Transcriptome of ansamitocin P-3 producer Actinosynnema pretiosum ATCC 31280

| PRJNA634364 | ENA

Transcriptome of Actinosynnema pretiosum ATCC 31280 under exogenous supplement of AP-3

Project description:In search of AP-3 resistant genes, ATCC 31280△ansaA (inactivation of ansamitocin pksA, in avoiding of the interruption of endogenous generated AP-3) were cultured under the addition of 0, 50, 100 and 200 mg/L exogenous AP-3 for 24 h and collected, for strains under 200 mg/L AP-3, samples after 48 h and 72 h were also collected, and the RNA samples were collected and sent for sequencing.

2019-11-06 | GSE139930 | GEO

Transcriptome of Actinosynnema pretiosum ATCC 31280 under exogenous supplement of AP-3

Project description:Transcriptome of Actinosynnema pretiosum ATCC 31280 under exogenous supplement of AP-3

| PRJNA587649 | ENA

Actinosynnema pretiosum

Project description:Actinosynnema pretiosum overview

| PRJNA124045 | ENA