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Homo sapiens

ABSTRACT: Human basal-like breast cancer cell line HCC1143 treated with BET inhibitor JQ1 in combination with MEK inhibitor Trametinib or PI3K/mTOR inhibitor BEZ235

PROVIDER: PRJNA323723 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR3605775.fastq.gz	Fastqsanger.gz
	SRR3605776.fastq.gz	Fastqsanger.gz
	SRR3605777.fastq.gz	Fastqsanger.gz
	SRR3605778.fastq.gz	Fastqsanger.gz
	SRR5573770.fastq.gz	Fastqsanger.gz

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Human basal-like breast cancer cell line HCC1143 treated with BET inhibitor JQ1 in combination with MEK inhibitor Trametinib or PI3K/mTOR inhibitor BEZ235

Project description:The goal of this experiment was to understand the changes in gene expression in the human basal-like breast cancer cell line HCC1143 following treatment with the MEK inhibitor Trametinib (T), PI3K/mTOR inhibitor BEZ235 (B), the BET inhibition JQ1 (JQ), Trametinib + JQ1 (TJ), or BEZ235 + JQ1(BJ), compared to a DMSO control (D). Samples were treated for 72hr and run in triplicate.

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