Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens strain:(YRI) Yoruba HapMap population

ABSTRACT: Whole genome sequencing of (YRI) Yoruba HapMap population

PROVIDER: PRJNA33865 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR003199_1.fastq.gz	Fastqsanger.gz
	ERR003199_2.fastq.gz	Fastqsanger.gz
	ERR003200_1.fastq.gz	Fastqsanger.gz
	ERR003200_2.fastq.gz	Fastqsanger.gz
	ERR003201_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 1382

Similar Datasets

Homo sapiens strain:(YRI) Yoruba HapMap population

Project description:CompleteGenomics sequencing of (YRI) Yoruba HapMap population

| PRJNA177963 | ENA

Homo sapiens strain:(YRI) Yoruba HapMap population

Project description:CompleteGenomics sequencing of (YRI) Yoruba HapMap population. DNA for sequencing was extracted from whole blood

| PRJNA196132 | ENA

Homo sapiens strain:(YRI) Yoruba in Ibadan Nigeria HapMap population

Project description:Exome sequencing of (YRI) Yoruba in Ibadan Nigeria HapMap population

| PRJNA59839 | ENA

Illumina HapMap YRI (1M-Duo)

Project description:HapMap YRI samples

2009-07-27 | GSE16896 | GEO

Genome-wide baseline microRNA expression quantification in HapMap phase I CEU and YRI samples

Project description:Baseline microRNA (miRNA) expression was evaluated in 107 HapMap lymphoblastoid cell lines (LCLs; 53 CEU and 54 YRI) using Exiqon miRCURY LNA arrays v10.0 (Exiqon array).

2012-07-29 | GSE34406 | GEO

4sU metabolic labeled transcripts in 65 YRI LCLs

Project description:Noncoding variants play a central role in the genetics of complex traits, but we still lack a full description of the main molecular pathways through which they act. Here we used molecular data to quantify the contribution of cis-acting genetic effects at each major stage of gene regulation from chromatin to proteins, within a population sample of Yoruba lymphoblastoid cell lines (LCLs). We performed 4sU metabolic labeled transcripts in 65 YRI LCLs to identify genetic variants that affect transcription rates. As expected, we found an important contribution of genetic variation via chromatin, contributing â¼65% of eQTLs (expression Quantitative Trait Loci). The remaining eQTLs, which are not asso- ciated with chromatin-level variation, are highly enriched in transcribed regions, and hence may affect expression through co- or post-transcriptional processes. International HapMap lymphoblastoid cell lines (LCLs) derived from YRI (Yoruba in Ibadan, Nigeria); We adapted the 4sU labelling method from (PMID 21516085). Briefly, cell cultures were grown to log phase in volumes sufficient to yield about 300 ng of 4sU-labeled RNA. Cells were incubated with 4sU for the required length of time (0, 30, or 60 minutes), then washed, pelleted, and frozen. Total RNA was extracted, and 4sU-labeled RNA was separated from total RNA using a bead-based biotin-streptavidin purification protocol. We sequenced metabolic labeled transcripts in 65 YRI LCLs 30 minutes and 60 minutes after incubation.

2016-03-29 | E-GEOD-75220 | biostudies-arrayexpress

Genome-wide baseline microRNA expression quantification in HapMap phase I CEU and YRI samples

Project description:Baseline microRNA (miRNA) expression was evaluated in 107 HapMap lymphoblastoid cell lines (LCLs; 53 CEU and 54 YRI) using Exiqon miRCURY LNA arrays v10.0 (Exiqon array). Total RNA from each of the 107 HapMap sample was labeled and hybridized onto an Exiqon array

2012-07-28 | E-GEOD-34406 | biostudies-arrayexpress

Genotyping of human lymphoblastoid cell lines from CEU and YRI HapMap individuals

Project description:Paired genomic DNA and cDNA samples obtained from lymphoblastoid cell lines from CEU and YRI HapMap individuals were hybridized to custom Illumina SNP arrays to study allele-specific expression in this tissue.

2010-03-02 | E-TABM-927 | biostudies-arrayexpress

Homo sapiens strain:(PJL) Punjabi HapMap population

Project description:Whole genome sequencing of (PJL) Punjabi HapMap population

| PRJNA59833 | ENA

Illumina HapMap YRI (HumanCNV100Wv1.0)

Project description:HapMap samples

2009-07-27 | GSE17214 | GEO