Gut metagenome
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA340483 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR5190124_1.fastq.gz | Fastqsanger.gz | |||
| SRR5190124_2.fastq.gz | Fastqsanger.gz |
Items per page: 5 1 - 2 of 2 |
Similar Datasets
Project description:Western lowland gorrila individual fecal microbial communities from Wisconsin, USA - Go1022B metagenome metagenome
| PRJNA340484 | ENA
Project description:Orangutan individual fecal microbial communities from fecal samples from Wisconsin, USA - O1111 metagenome metagenome
| PRJNA340487 | ENA
Project description:Orangutan group fecal microbial communities from Wisconsin, USA - O827 metagenome metagenome
| PRJNA340485 | ENA
Project description:Capybara group fecal microbial communities from Wisconsin, USA - P827 metagenome metagenome
| PRJNA340521 | ENA
Project description:Capybara group fecal microbial communities from Wisconsin, USA - P1105 metagenome metagenome
| PRJNA340522 | ENA
Project description:Orangutan group fecal microbial communities from fecal samples from Wisconsin, USA - O1105 metagenome metagenome
| PRJNA340486 | ENA
Project description:Fermenting microbial communities generate hydrogen: its removal through production of acetate, methane, or hydrogen sulfide modulates the efficiency of energy extraction from available nutrients in many ecosystems. We noted that pathway components for acetogenesis are more abundantly and consistently represented in the gut microbiomes of monozygotic twins and their mothers than components for methanogenesis or sulfate reduction, and subsequently analyzed the metabolic potential of two sequenced human gut acetogens, Blautia hydrogenotrophica and Marvinbryantia formatexigens in vitro and in the intestines of gnotobiotic mice harboring a prominent saccharolytic bacterium. To do so, we developed a generally applicable method for multiplex sequencing of expressed microbial mRNAs, and together with mass spectrometry of metabolites, show that these organisms have distinct patterns of substrate utilization. B. hydrogenotrophica targets aliphatic and aromatic amino acids. It increases the efficiency of fermentation by consuming reducing equivalents, thereby maintaining a high NAD+/NADH ratio and boosting acetate production. In contrast, M. formatexigens consumes oligosaccharides, does not impact the redox state of the gut, and boosts the yield of succinate. These findings have strategic implications for those who wish to manipulate the hydrogen economy of gut microbial communities in ways that modulate energy harvest. 119 Samples consisting of Bacteroides thetaiotaomicron, Marvinbryantia formatexigens, and Blautia hydrogenotrophica cecal and fecal samples. Please see the individual Sample descriptions for more information.
2010-05-21 | E-GEOD-21906 | biostudies-arrayexpress
Project description:Ring-tailed lemur group fecal microbial communities from Wisconsin, USA - L827 metagenome metagenome
| PRJNA340523 | ENA
Project description:Ring-tailed lemur group fecal microbial communities from Wisconsin, USA - L1105 metagenome metagenome
| PRJNA340524 | ENA
Project description:The gut microbiota is closely associated with digestion, metabolism, immunity, and host health. The imbalance of the microbial community in livestock directly affects their well-being and, consequently, productivity. The composition and diversity of the gut microbiota are influenced not only by host genetics but also by environmental factors such as the microbial complexity of the rearing environment, feeds, and antibiotics. Here, we focus on the comparison of gut microbial communities in miniature pigs developed for xenotransplantation in specific pathogen-free (SPF) and conventional (non-SPF) facilities. To identify the disparities in gut microbial composition and functionality between these two environments, 16S RNA metagenome sequencing was conducted using fecal samples. The results revealed that the non-SPF pigs had higher gut microbiota diversity than the SPF pigs. The genera Streptococcus and Ruminococcus were more abundant in SPF pigs than in non-SPF pigs. Blautia, Bacteroides, and Roseburia were exclusively observed in SPF pigs, whereas Prevotella was exclusively found in non-SPF pigs. Carbohydrate and nucleotide metabolism, as well as environmental information processing, were predicted to be enriched in SPF pigs. In addition, energy and lipid metabolism, along with processes related to genetic information, cellular communication, and diseases, were predicted to be enriched in non-SPF pigs. This study makes an important contribution to elucidating the impact of environments harboring a variety of microorganisms, including pathogens, on the gut microbiota of miniature pigs. Furthermore, we sought to provide foundational data on the characteristics of the gut microbiota in genetically modified pigs, which serve as source animals for xenotransplantation.
2024-04-22 | GSE264183 | GEO