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Dorea longicatena

ABSTRACT: Normal gut bacterium

PROVIDER: PRJNA35001 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
		Other
	SRR275643.fastq.gz	Fastqsanger.gz
	SRR896017_1.fastq.gz	Fastqsanger.gz
	SRR896017_2.fastq.gz	Fastqsanger.gz

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Red Meat Intake, Indole-3-Acetate, and <i>Dorea longicatena</i> Together Affect Insulin Resistance after Gastric Bypass.

Project description:Roux-en-Y Gastric bypass (RYGB) promotes improvement in type 2 diabetes (T2D) shortly after surgery, with metabolic mechanisms yet to be elucidated. This study aimed to investigate the relationship between food intake, tryptophan metabolism, and gut microbiota on the glycemic control of obese T2D women after RYGB surgery. Twenty T2D women who underwent RYGB were evaluated before and three months after surgery. Food intake data were obtained by a seven-day food record and a food frequency questionnaire. Tryptophan metabolites were determined by untargeted metabolomic analysis, and the gut microbiota was determined by 16S rRNA sequencing. The glycemic outcomes were fasting blood glucose, HbA1C, HOMA-IR, and HOMA-beta. Linear regression models were applied to assess the associations between the changes in food intake, tryptophan metabolism, and gut microbiota on glycemic control after RYGB. All variables changed after RYGB (p < 0.05), except for tryptophan intake. Jointly, the variation in red meat intake, plasma indole-3-acetate, and Dorea longicatena was associated with postoperative HOMA-IR {R2 0.80, R2 adj 0.74; p < 0.01}. Red meat intake decreased three months after bariatric surgery while indole-3-acetate and Dorea longicatena increased in the same period. These combined variables were associated with better insulin resistance in T2D women after RYGB.

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Dorea longicatena AGR2136

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Dorea longicatena TSDC17.1-1.3

Project description:Strain Dorea longicatena TSDC17.1-1.3 (species Dorea longicatena) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0 and 49). The species name was assigned by genome clustering.

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Project description:Strain Dorea longicatena TSDC17.1-1.1 (species Dorea longicatena) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0 and 49). The species name was assigned by genome clustering.

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Project description:Strain Dorea longicatena TSDC10.2-1.2 (species Dorea longicatena) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0 and 42). The species name was assigned by genome clustering.

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Dorea longicatena TSDC10.2-1.3

Project description:Strain Dorea longicatena TSDC10.2-1.3 (species Dorea longicatena) was isolated from the fecal microbiota of a USA female at time point zero (bacterial isolates were sequenced from this donor on day 0 and 42). The species name was assigned by genome clustering.

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