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Identification of differentially expressed miRNAs between SW480 and SW620 spheroid cultures

ABSTRACT: Identification of differentially expressed miRNAs between SW480 and SW620 spheroid cultures

PROVIDER: PRJNA352464 | ENA |

REPOSITORIES: ENA

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Identification of differentially expressed miRNAs between SW480 and SW620 spheroid cultures [miRNA]

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Identification of differentially expressed genes between SW480 and SW620 spheroid cultures [mRNA]

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Identification of differentially expressed miRNAs between SW480 and SW620 spheroid cultures

Project description:This SuperSeries is composed of the SubSeries listed below.

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MicroRNA expression profile between human colorectal cancer SW480 and SW620 cell line

Project description:Two isogenic human colorectal cancer cell lines (primary SW480 cell line and its lymph node metastatic variant SW620 cell line),as an in vitro metastatic model. We have demonstrated that SW620 cell line possesses high metastasis potential and SW480 cell linepossesses low metastatic potential. We want to compare the whole cell microRNAs profiles of two isogenic colorectal cancer cell lines (SW480 and SW620 cell line), to gain an insight into the molecular events of colon cancer metastasis.

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24h time-course microarray study of SW480 and SW620 cells

Project description:A 24h time-course array study was performed to analyse the different circadian phenotypes of SW480 and SW620 cells, a cell line from a primary tumor and a metastatic cell line from the same patient. Samples were taken every three hours for a period of 24h so that 9 time-points could be analysed for each cell line.

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