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Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

ABSTRACT: Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

OTHER RELATED OMICS DATASETS IN: GSE92247

PROVIDER: PRJNA357025 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5097960.fastq.gz	Fastqsanger.gz
	SRR5097970.fastq.gz	Fastqsanger.gz
	SRR5097980.fastq.gz	Fastqsanger.gz
	SRR5097961.fastq.gz	Fastqsanger.gz
	SRR5097971.fastq.gz	Fastqsanger.gz

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Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

Project description:Pluripotent stem cell-derived cardiomyocytes (PSC-CMs) were transplanted into rats for one month to determine the change in morphology, structure, and function. Single cell RNA seq analysis was performed to compared the transcriptome of in vivo matured PSC-CMs to adult rat cardiomyocytes and in vitro cultured PSC-CMs.

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Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.

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