Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Pediatric spondyloarthritis patients versus healthy controls

PROVIDER: PRJNA362958 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5196130_1.fastq.gz	Fastqsanger.gz
	SRR5196130_2.fastq.gz	Fastqsanger.gz
	SRR5196140_1.fastq.gz	Fastqsanger.gz
	SRR5196140_2.fastq.gz	Fastqsanger.gz
	SRR5196150.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 58

Similar Datasets

Massive Parallel Sequencing (MPS) of miRNAs in PBMCs

Project description:We carried out Massive Parallel Sequencing (MPS) to reveal circulating miRNA profiles of 96 patients to distinguish the radiographic and non-radiographic axial spondyloarthritis. The sequencing platform identified 1900 miRNA species, out of which 432 miRNAs were present with the base mean, computed by DESeq2, more than 10. We identified 48 miRNAs, which were different in PBMCs in patients with axial spondyloarthritis compared to healthy controls.

2024-01-09 | GSE252708 | GEO

Gene expression in juvenile spondyloarthritis

Project description:Association of juvenile spondyloarthritis (jSpA) with the HLA-B27 genotype is well established, but there is little knowledge of other genetic factors with a role in disease development. The aim of the present study was to identify and confirm gene signatures and novel biomarkers in various cohorts of untreated and treated patients diagnosed with jSpA and other forms of juvenile idiopathic arthritis (JIA). DNA microarray gene expression was performed in 11 patients with jSpA and in four healthy controls, along with bioinformatics analysis of retrieved data (DAVID, GSEA, IPA).

2014-10-31 | GSE58667 | GEO

Sclerotic-type chronic graft-versus-host disease exhibits enrichment of Th1 and TSLP-OX40 cytokines

Project description:In this study we performed the first global RNA-seq analysis in pediatric to young-adult patients with sclerotic-type graft-versus-host disease/scGvHD (n=7), age- and sex-matched to 8 healthy controls and 10 patients with atopic dermatitis/AD. Differentially expressed genes (DEGs) were defined based on fold changes/FCH>1.5 and false discovery rate/FDR<0.05 criteria. We found robust and significant Th1 (e.g. CXCR9/10/11, IFNG) and OX40-skewing in ScGvHD (e.g. OX40L, TLSP, IL-33) that sometimes exceeded that in AD and was validated on RT-PCR.

2023-10-11 | GSE230200 | GEO

Homo sapiens

Project description:RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls

| PRJNA388098 | ENA

Epigenetic profiling of Fetal Alcohol Spectrum Disorder (FASD) Replication

Project description:Genome wide DNA methylation profiling of FASD patients versus healthy unexposed controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 28 healthy controls and7 FASD patients.

2019-03-18 | GSE113012 | GEO

RNAseq of pedriatic IBD and XIAP-deficient biopsy samples

Project description:Deficiency in the X-linked inhibitor of apoptosis protein (XIAP) is the cause for the X-linked lymphoproliferative syndrome 2 (XLP2). About one third of all patients suffers from severe and therapy refractory inflammatory bowel disease (IBD), but the exact pathogenesis remains undefined. We examined the differences in gene expression of pediatric XLP2 patients with IBD to healthy controls and pediatric IBD patients.

2021-09-20 | GSE183069 | GEO

Epigenetic profiling of Fetal Alcohol Spectrum Disorder (FASD) Discovery

2019-03-18 | GSE112987 | GEO

Effect of Age on Severity and Recovery of Acute Multiple Sclerosis Attack

Project description:Pediatric MS patients suffer from severe first and second relapse but better recovery explained by difference in age-restricted transcriptional profiles associated with antigen-presentation and B-cell activation Herein, we compared the blood mononuclear cell transcriptome of pediatric and adult MS patients with recovery (PDMS-rec, ADMS-rec) and without recovery (PDMS-norec, ADMS-norec) 6 months after relapse. Healthy pediatric and adult subjects (PDC, ADC) were used as controls.

2021-01-27 | GSE146383 | GEO

Project description:Fecal metabolomics in pediatric spondyloarthritis

| PRJNA342486 | ENA

Homo sapiens

Project description:Expression data from mesenchymal stromal cells derived from pediatric leukemia patients and healthy pediatric controls

| PRJNA394243 | ENA