Project description:Dam, the most described bacterial DNA-methyltransferase, is widespread in gamma-proteobacteria. Dam DNA methylation can play a role in various genes expression and is involved in pathogenicity of several bacterial species. In the entomopathogenic bacterium Photorhabdus luminescens, a dam ortholog was identified. Overexpression of dam in P. luminescens did not impair growth ability in vitro. In contrast, compared to a control strain harboring an empty plasmid, a significant decrease in motility was observed in the dam-overexpressing strain. In addition, the dam-overexpressing P. luminescens strain showed a delayed virulence compared to that of the control strain after injection in larvae of the lepidopteran Spodoptera littoralis. These results reveal that Dam plays a major role during P. luminescens insect infection.

2017-10-04 | GSE100650 | GEO

Photorhabdus luminescens subsp. luminescens ATCC 29999

Project description:Photorhabdus luminescens subsp. luminescens ATCC 29999 Genome sequencing

| PRJNA210920 | ENA

Photorhabdus luminescens strain:PB45.5

Project description:Photorhabdus luminescens strain:PB45.5 Genome sequencing and assembly

| PRJNA296855 | ENA