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Peptacetobacter hiranonis

ABSTRACT: Clostridium hiranonis overview

PROVIDER: PRJNA37523 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
		Other
	SRR005461.fastq.gz	Fastqsanger.gz
	SRR036121.fastq.gz	Fastqsanger.gz
	SRR036122.fastq.gz	Fastqsanger.gz
	SRR036123.fastq.gz	Fastqsanger.gz

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Peptacetobacter hiranonis

Project description:Peptacetobacter hiranonis assembly

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Correlation between <i>Peptacetobacter hiranonis</i>, the <i>baiCD</i> Gene, and Secondary Bile Acids in Dogs.

Project description:Bile acid metabolism is a key pathway modulated by intestinal microbiota. Peptacetobacter (Clostridium) hiranonis has been described as the main species responsible for the conversion of primary into secondary fecal unconjugated bile acids (fUBA) in dogs. This multi-step biochemical pathway is encoded by the bile acid-inducible (bai) operon. We aimed to assess the correlation between P. hiranonis abundance, the abundance of one specific gene of the bai operon (baiCD), and secondary fUBA concentrations. In this retrospective study, 133 fecal samples were analyzed from 24 dogs. The abundances of P. hiranonis and baiCD were determined using qPCR. The concentration of fUBA was measured by gas chromatography-mass spectrometry. The baiCD abundance exhibited a strong positive correlation with secondary fUBA (ρ = 0.7377, 95% CI (0.6461, 0.8084), p < 0.0001). Similarly, there was a strong correlation between P. hiranonis and secondary fUBA (ρ = 0.6658, 95% CI (0.5555, 0.7532), p < 0.0001). Animals displaying conversion of fUBA and lacking P. hiranonis were not observed. These results suggest P. hiranonis is the main converter of primary to secondary bile acids in dogs.

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Peptacetobacter hiranonis DSM 13275

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Peptacetobacter hiranonis strain:ASCUSCA136

Project description:Peptacetobacter hiranonis strain:ASCUSCA136 Genome sequencing

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Complete Genome Sequence of Peptacetobacter (Clostridium) hiranonis Strain DGF055142, Isolated from Dog Feces from Flagstaff, Arizona, USA, 2019.

Project description:A single-chromosome closed genome of Peptacetobacter (Clostridium) hiranonis strain DGF055142 was generated using Illumina MiSeq short reads paired with Oxford Nanopore MinION long reads. This isolate was obtained from a canine in Flagstaff, Arizona, in 2019. Peptacetobacter (C.) hiranonis was hypothesized to contribute to canine Clostridium difficile infection resistance.

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Peptacetobacter hiranonis strain:DSM 13275

Project description:Peptacetobacter hiranonis strain:DSM 13275 Genome sequencing and assembly

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