Project description:Transcriptional profiling of mouse embryonic stem cells comparing control (dCas9 transfected) ES cells with ES cells transfected with a Hottip promoter gRNAs and Hoxa13 promoter gRNAs along with dCAs9-VP160. Goal was to determine the effects of activation of Hottip lncRNA and Hoxa13 on expression of Hox genes
Project description:RNA-seq of mouse sciatic peripheral nerve of injured mouse with implant: control (untreated) vs local delivery of MCC950 (NLRP3inh) vs standard FBR treatment dexamethasone (Dex). .