Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: Ankylosing spondylitis immune project

PROVIDER: PRJNA378893 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14416633.fastq.gz	Fastqsanger.gz
	SRR14416634.fastq.gz	Fastqsanger.gz
	SRR14416635.fastq.gz	Fastqsanger.gz
	SRR14416636.fastq.gz	Fastqsanger.gz
	SRR14416637.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 84

Similar Datasets

Homo sapiens

Project description:Ankylosing spondylitis vs control synovial biopsies

| PRJNA177731 | ENA

Differentially Expressed Genes in Males and Females with Ankylosing Spondylitis (AS): Discrete Effectors in IL-17-producing Cells of Patients with AS.

Project description:To compare differential effectors of IL-17 pathway between male and female patients with ankylosing spondylitis (AS)

2023-01-02 | GSE221786 | GEO

Single cell RNAseq of ankylosing spondylitis lymphocytes from peripheral blood and synovial fluid

Project description:Single-cell transcriptome of >55,000 cells multiplexed into 4 channels obtained from peripheral blood and synovial fluid of two patients with HLA-B27+ ankylosing spondylitis,.

2021-10-18 | E-MTAB-10948 | biostudies-arrayexpress

Homo sapiens

Project description:Screening genes associated with rheumatoid arthritis and ankylosing spondylitis

| PRJNA170865 | ENA

Homo sapiens

Project description:Sexual Dimorphism in the Th17 Signature of Ankylosing Spondylitis

| PRJNA297828 | ENA

WTCCC2 Ankylosing spondylitis cases - individual

Project description:WTCCC1 project Ankylosing Spondylitis (AS) samples

| EGAD00000000010 | EGA

Single-cell TCR sequencing of in vitro peripheral blood cell stimulation in ankylosing spondylitis

Project description:Single-cell TCR sequencing of in vitro DCs (DC-C96car) stimulated CD4+ T cell single cell TCR sequencing in ankylosing spondylitis

2022-06-29 | GSE207037 | GEO

Project description:WTCCC2 project samples from Ankylosing spondylitis Cohort

| EGAD00010000150 | EGA

Control vs. PGISp spine samples

Project description:OBJECTIVES: Ankylosing spondylitis (AS) is unique in its pathology where inflammation commences at the entheses before progressing to an osteoproliferative phenotype generating excessive bone formation that can result in joint fusion. The underlying mechanisms of this progression are poorly understood. Using the proteoglycan-induced spondylitis mouse (PGISp) model which displays spondylitis and eventual joint fusion following an initial inflammatory stimulus, we have characterised the structural and molecular changes that underlie disease progression METHODS: PGISp mice were characterised 12 weeks after initiation of inflammation using expression profiling. RESULTS: Microarray profiling showed genes involved in inflammation and immune-regulation were altered. Further, a number of genes specifically involved in bone regulation including other members of the Wnt pathway were also dysregulated. CONCLUSION: This study implicates the Wnt pathway as a likely mediator of the mechanism by which inflammation induces bony ankylosis in spondyloarthritis, raising the potential that therapies targeting this pathway may be effective in preventing this process. 4 unaffected spines vs. 4 spines from PGISp-affected mice

2012-11-15 | E-GEOD-41039 | biostudies-arrayexpress

Homo sapiens

Project description:Expression profiling in whole blood in ankylosing spondylitis patients and controls

| PRJNA134725 | ENA