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Rattus norvegicus

ABSTRACT: Gene expression profiles of cardiomyocytes infected with Ad-CaMKII-delta 2 or Ad-CaMKII-delta 9 over Ad-lacZ

PROVIDER: PRJNA381329 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5406940_1.fastq.gz	Fastqsanger.gz
	SRR5406940_2.fastq.gz	Fastqsanger.gz
	SRR5406941_1.fastq.gz	Fastqsanger.gz
	SRR5406941_2.fastq.gz	Fastqsanger.gz
	SRR5406942_1.fastq.gz	Fastqsanger.gz

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Rattus norvegicus

Project description:Expression data from Ad-atrogin-1-GFP or Ad-GFP infected cardiomyocytes

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Project description:Expression data from Ad-β-catenin-GFP or Ad-GFP infected cardiomyocytes

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Expression profiling of p53-regulated genes by cDNA microarray analysis

Project description:To characterize the molecular features of p53 signaling pathway, we generated the gene-expression profiles of p53-introduced U373MG cells by genome-wide cDNA microarrays Keywords: time course U373MG cells were infected with 20 MOI of Ad-p53 or Ad-LacZ. mRNA from infected cells were collected at 0h, 6h, 12h, 24h and 48h. we used the RNA mixtures from Ad-LacZ infected cells as a reference of cDNA microarray analysis.

2010-05-05 | E-GEOD-14953 | biostudies-arrayexpress

Primary hepatocyte transcriptional response to Fis1 and Drp1 over-expression by adenovirus

Project description:RNA-seq analysis of Ad-LacZ, Ad-Fis1 and Ad-Drp1 infected primary hepatocyte.

2021-03-26 | GSE169630 | GEO

Primary hepatocyte transcriptional response to Mfn2 over-expression by adenovirus

Project description:RNA-seq analysis of Ad-LacZ, Ad-Mfn2 infected primary hepatocyte.

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Primary hepatocyte transcriptional response to Pink1 over-expression by adenovirus

Project description:RNA-seq analysis of Ad-LacZ, Ad-Pink1 infected primary hepatocyte.

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Patterns of Gastrointestinal Helminth Infections in Rattus rattus, Rattus norvegicus, and Mus musculus in Chile

Project description:Few studies have assessed the patterns of parasite populations of rodents over a longitudinal gradient in Chile. In this work, the gastrointestinal helminthic fauna of invasive rodents in Chile was examined to assess the association between their presence/absence and abundance with latitude, host sex, and host body condition, and to assess the coexistence and correlation of the abundance between parasite species. Rodents were obtained from 20 localities between 33 and 43°S. Helminths were extracted from the gastrointestinal tract and identified morphologically. Overall, 13 helminth taxa were obtained. The most frequently identified parasite species was Heterakis spumosa, and the most abundant was Syphacia muris, while Physaloptera sp. was the most widely distributed. No locality presented with a coexistence that was different from that expected by chance, while the abundance of five helminthic species correlated with the abundance of another in at least one locality, most likely due to co-infection rather than interaction. Host sex was associated with parasite presence or abundance, and female sex-biased parasitism was notably observed in all cases. Body condition and latitude presented either a positive or negative association with the presence or abundance of parasites depending on the species. It is notable that the likely native Physaloptera sp. is widely distributed among invasive rodents. Further, gravid females were found, suggesting spillback of this species to the native fauna. The low frequency and abundance of highly zoonotic hymenolepid species suggest that rodents are of low concern regarding gastrointestinal zoonotic helminths.

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Rattus norvegicus

Project description:Binding Profiles of Myc and RNA Polymerase II in Rat Neonatal Cardiomyocytes

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The social life of Norway rats (Rattus norvegicus).

Project description:The Norway rat has important impacts on our life. They are amongst the most used research subjects, resulting in ground-breaking advances. At the same time, wild rats live in close association with us, leading to various adverse interactions. In face of this relevance, it is surprising how little is known about their natural behaviour. While recent laboratory studies revealed their complex social skills, little is known about their social behaviour in the wild. An integration of these different scientific approaches is crucial to understand their social life, which will enable us to design more valid research paradigms, develop more effective management strategies, and to provide better welfare standards. Hence, I first summarise the literature on their natural social behaviour. Second, I provide an overview of recent developments concerning their social cognition. Third, I illustrate why an integration of these areas would be beneficial to optimise our interactions with them.

| S-EPMC7145424 | biostudies-literature

Kobuviruses carried by Rattus norvegicus in Guangdong, China.

Project description:BackgroundMurine kobuviruses (MuKV) are newly recognized picornaviruses first detected in murine rodents in the USA in 2011. Little information on MuKV epidemiology in murine rodents is available. Therefore, we conducted a survey of the prevalence and genomic characteristics of rat kobuvirus in Guangdong, China.ResultsFecal samples from 223 rats (Rattus norvegicus) were collected from Guangdong and kobuviruses were detected in 12.6% (28) of samples. Phylogenetic analysis based on partial 3D and complete VP1 sequence regions showed that rat kobuvirus obtained in this study were genetically closely related to those of rat/mouse kobuvirus reported in other geographical areas. Two near full-length rat kobuvirus genomes (MM33, GZ85) were acquired and phylogenetic analysis of these revealed that they shared very high nucleotide/amino acids identity with one another (95.4%/99.4%) and a sewage-derived sequence (86.9%/93.5% and 87.5%/93.7%, respectively). Comparison with original Aichivirus A strains, such human kobuvirus, revealed amino acid identity values of approximately 80%.ConclusionOur findings indicate that rat kobuvirus have distinctive genetic characteristics from other Aichivirus A viruses. Additionally, rat kobuvirus may spread via sewage.

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