Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Streptomyces tsukubensis strain:NRRL 18488

ABSTRACT: Streptomyces tsukubensis strain:NRRL 18488 Genome sequencing

PROVIDER: PRJNA382016 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Streptomyces tsukubensis strain:L20

Project description:Streptomyces tsukubensis strain:L20 Genome sequencing

| PRJNA702039 | ENA

Streptomyces tsukubensis NRRL18488

Project description:Streptomyces tsukubensis NRRL18488 Genome sequencing

| PRJNA76771 | ENA

Streptomyces tsukubensis strain:AT3

Project description:Streptomyces tsukubensis strain:AT3 Genome sequencing and assembly

| PRJNA577407 | ENA

Streptomyces tsukubensis strain:VKM Ac-2618D

Project description:Streptomyces tsukubensis strain:VKM Ac-2618D Genome sequencing and assembly

| PRJNA520973 | ENA

Ribosome pausing at the AT-rich codons regulates the protein expression of secondary metabolite gene clusters in the Streptomyces tsukubaensis NRRL 18488

Project description:Streptomyces tsukubaensis NRRL 18488 is the preferred strain for the production of immunosuppressant agent tacrolimus (FK506). To take full advantage of its genetic potential, systematic understanding of secondary metabolism and related regulatory mechanisms is highly demanded. Here, to this end, we complete its 7.9 Mbp linear genome sequence followed by integrating with multi-omics measurements. With accurate reannotation of FK506 gene cluster, total 2,389 transcription start sites were determined by using primary transcriptome analysis. Integrated analysis of transcriptome and translatome data revealed that secondary metabolic gene clusters, especially FK506 cluster, undergo translational control with decrease in translational efficiency according to the growth. Furthermore, we demonstrated that SD motif has little correlation with ribosome pausing but AT-rich codons delay the translational elongation. Strong ribosome pausing was observed in the rare TTA codon in FK506 cluster. This comprehensive genome-scale analysis provides insight to the translational regulation of secondary metabolism in S. tsukubaensis.

2019-10-16 | GSE97637 | GEO

Streptomyces ficellus strain:NRRL 8067

Project description:Streptomyces ficellus strain:NRRL 8067 Genome sequencing

| PRJNA507930 | ENA

Expression analysis of Candida tenuis NRRL Y-1498 grown in glucose or xylose

Project description:Investigation of whole genome gene expression level changes in Candida tenuis NRRL Y-1498 grown aerobically in xylose, compared to the same strain grown aerobically in glucose.

2011-10-20 | GSE24856 | GEO

Expression analysis of Lodderomyces elongisporus NRRL YB-4239 grown in glucose or xylose

Project description:Investigation of whole genome gene expression level changes in Lodderomyces elongisporus NRRL YB-4239 grown aerobically in xylose, compared to the same strain grown aerobically in glucose.

2011-10-20 | GSE24855 | GEO

Expression analysis of Spathaspora passalidarum NRRL Y-27907 grown in glucose or xylose

Project description:Investigation of whole genome gene expression level changes in Spathaspora passalidarum NRRL Y-27907 grown aerobically in xylose, compared to the same strain grown aerobically in glucose.

2011-10-20 | GSE24853 | GEO

Streptomyces toyocaensis strain:NRRL 15009

Project description:Streptomyces toyocaensis strain:NRRL 15009 Genome sequencing and assembly

| PRJNA239004 | ENA