Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Human gut metagenome

ABSTRACT: colorectal cancer microbial_community diversity

PROVIDER: PRJNA383606 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5460300_1.fastq.gz	Fastqsanger.gz
	SRR5460300_2.fastq.gz	Fastqsanger.gz
	SRR5460310_1.fastq.gz	Fastqsanger.gz
	SRR5460310_2.fastq.gz	Fastqsanger.gz
	SRR5460320_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 260

Similar Datasets

human gut metagenome

Project description:colorectal cancer microbial community diversity

| PRJNA383605 | ENA

human gut metagenome

Project description:Colorectal cancer patients Targeted Locus (Loci)

| PRJNA238277 | ENA

human gut metagenome

Project description:bacterial diversity of colorectal adenoma raw sequence reads

| PRJNA297487 | ENA

human gut metagenome

Project description:Gut metagenomes of patients with colorectal cancer

| PRJNA397219 | ENA

human gut metagenome

Project description:Raw Sequence Reads of Colorectal Cancer Patients

| PRJNA797640 | ENA

human gut metagenome

Project description:human gut microbiome in colorectal cancer Egyptians patients

| PRJNA895360 | ENA

human gut metagenome

Project description:Malaysia (MAL1) Cohort of Colorectal Cancer Patients with and without Biofilm Formation

| PRJNA325649 | ENA

human gut metagenome

Project description:Malaysia (MAL2) Cohort of Colorectal Cancer Patients with and without Biofilm Formation

| PRJNA325650 | ENA

Relating human gut metagenome and metaproteome

Project description:Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and shotgun metaproteomics. We found a considerable divergence between genetic potential and functional activity of the human healthy gut microbiota, in spite of a quite comparable taxonomic structure revealed by the two approaches. Investigation of inter-individual variability of taxonomic features revealed Bacteroides and Akkermansia as remarkably conserved and variable in abundance within the population, respectively. Firmicutes-driven butyrogenesis (mainly due to Faecalibacterium spp.) was shown to be the functional activity with the higher expression rate and the lower inter-individual variability in the study cohort, highlighting the key importance of the biosynthesis of this microbial by-product for the gut homeostasis. The taxon-specific contribution to functional activities and metabolic tasks was also examined, giving insights into the peculiar role of several gut microbiota members in carbohydrate metabolism (including polysaccharide degradation, glycan transport, glycolysis and short-chain fatty acid production). In conclusion, our results provide useful indications regarding the main functions actively exerted by the gut microbiota members of a healthy human cohort, and support metaproteomics as a valuable approach to investigate the functional role of the gut microbiota in health and disease.

2017-07-19 | PXD005780 | Pride

human metagenome

Project description:Colorectal Cancer Metagenome

| PRJNA178500 | ENA