Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole Exome Sequencing of Uveal Melanoma

ABSTRACT: Whole Exome Sequencing of Uveal Melanoma

PROVIDER: PRJNA386839 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Whole exome sequencing of human primary uveal melanomas

Project description:Primary uveal melanomas show multiple genetic alterations. To determine mutational status of six human primary uveal melanomas, we performed whole exome sequencing (WES) and called Single Nucleotide Polimorphism (SNPs) to identify somatic mutations in these human primary uveal melanomas.

2021-01-25 | GSE138664 | GEO

Whole exome sequencing and methylation profiling of uveal melanoma

Project description:Whole exome sequencing and methylation profiling of uveal melanoma

| PRJNA397242 | ENA

Whole-exome sequencing and targeted DNA sequencing of matched ocular melanocytosis and uveal melanoma

Project description:Whole-exome sequencing and targeted DNA sequencing of matched ocular melanocytosis and uveal melanoma

| PRJNA545748 | ENA

Whole-exome sequencing and targeted DNA sequencing of matched ocular melanocytosis and uveal melanoma

Project description:Whole-exome sequencing and targeted DNA sequencing of matched ocular melanocytosis and uveal melanoma

| PRJNA545749 | ENA

Whole exome sequencing of human primary uveal melanomas

Project description:Whole exome sequencing of human primary uveal melanomas

| PRJNA576696 | ENA

Exome sequencing of uveal melanoma

Project description:Exome capture identifies recurrent somatic mutations in EIF1AX and SF3B1 anti-correlated in uveal melanoma with disomy 3

| PRJEB3979 | ENA

Transcriptome analysis reveals key dysregulated transcriptional programmes in uveal melanoma

Project description:In this study, we conducted whole-transcriptome sequencing in five primary Uveal Melanoma and four adjacent tissues to uncover key dysregulated the gene-regulatory circuits in Uveal Melanoma.

2023-11-08 | GSE211763 | GEO

Whole-transcript expression data for uveal melanoma

Project description:G protein alpha q and 11 are mutated in 90% of uveal melanoma and they activate the MAPK pathway. Using expression microarray analysis, we identified a unique MEK dependent transcriptional signature with genes that are involved in proliferation and tumor cell invasion. Uveal melanoma cells were profiled on Illumina Human HT-12 arrays per manufacturer's instructions

2011-12-31 | E-GEOD-33655 | biostudies-arrayexpress

Whole-transcript expression data of BRD4 inhibition in uveal melanoma

Project description:G protein alpha q and 11 are mutated in 80% of uveal melanoma. We observed that treatment with the BRD4 inhibitor JQ1 resulted in different phenotypic responses in G-protein mutant uveal melanoma cell lines and wild type uveal melanoma cell lines. We used microarrarys to profile the gene expression changes occuring in wild type and mutant cell lines in response to treament with JQ1 Uveal melanoma cells were profiled in triplicate on Affymetrix Human Genome U133A 2.0 Array arrays per manufacturer's instructions

2015-02-19 | E-GEOD-66048 | biostudies-arrayexpress

Whole Exome Sequencing of Uveal Melanoma

Project description:<p>Uveal melanoma is a rare form of melanoma that occurs in the eye and has no effective treatment once metastatic. To further characterize the genomic events driving uveal melanoma, whole exome sequencing was performed on 61 primary tumors derived from enucleations, 3 liver metasases, and paired normal DNA. Recurrent somatic genetic alterations including point mutations, small insertions and deletions, as well as copy number variations were identified. In addition, RNA sequencing of uveal melanoma cell lines expressing shRNAs was performed from total RNA as well as polysome-associated mRNA in order to identify transcripts regulated by EIF1AX at the level of translation.</p>

| phs001370 | dbGaP

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data