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B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line

ABSTRACT: B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line

PROVIDER: PRJNA390731 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5656180.fastq.gz	Fastqsanger.gz
	SRR5656181.fastq.gz	Fastqsanger.gz
	SRR5656182.fastq.gz	Fastqsanger.gz
	SRR5656177.fastq.gz	Fastqsanger.gz
	SRR5656178.fastq.gz	Fastqsanger.gz

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Project description:Microarray profiling of Burkitt Lymphoma cell line (BL2) with B-cell activating factor (BAFF) for 24 hrs . The Burkitt Lymphoma cell line were either only cultured in cell culture medium supplemented with 10 mM HEPES at 1 × 106 cells/ml or additionally incubated with B-cell activating factor (BAFF) for 24 hrs

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Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:The purpose of the study was to identify downstream gene targets regulated by a new alternative splice of BAFF (B-Cell Activating factor belonging to the TNF Family) that we called Delta4-BAFF (because it characterized by an alternative splice of exon 4). To do this we used human burkitt's lymphoma cell line (RAMOS) stably transfected with Delta4-BAFF or stably transfected with Delta4-BAFF mutated on its N-glycosylation site (Delta4-BAFF-N124D). One control was used : RAMOS stably transfected with empty vector (pIRES2-GFP from Clontech)

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