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Tetzosporium hominis strain:VT-49

ABSTRACT: Tetzosporium hominis strain:VT-49 Genome sequencing and assembly

PROVIDER: PRJNA393394 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	NOKQ01.dat.gz	Other
	NOKQ01.fasta.gz	Fasta.gz
	NOKQ01.master.dat	Other
	NOKQ01.dat.gz	Other

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Proteomic profiling of clinical isolates and reference strain of H-34 Mycoplasma hominis to study phenotypic adaptation

Project description:Mycoplasma hominis (M. hominis) belongs to the class Mollicutes, characterized by a very small genome size, metabolic pathway reduction, including transcription factors, and the absence of a cell wall. Despite this, they adapt well not only to specific niches within the host organism but can also spread throughout the body, colonizing various organs and tissues. The mechanisms of adaptation in M. hominis, as well as the pathways regulating them, are poorly understood. It is known that when adapting to adverse conditions, mycoplasmas can undergo phenotypic switches that may persist for several generations. To investigate the adaptive properties of M. hominis associated with survival in the host organism, we conducted a comparative proteogenomic analysis of 8 clinical isolates of M. hominis obtained from patients with urogenital infections, along with the laboratory strain H-34.

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Cell wall-deficient Mycoplasma hominis represses biofilm formation of uropathogenic Escherichia coli.

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Enterococcus faecalis strain:VT-H1 | isolate:VT-H1

Project description:Enterococcus faecalis strain:VT-H1 | isolate:VT-H1 Genome sequencing

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Cell wall-deficient Mycoplasma hominis represses biofilm formation of uropathogenic Escherichia coli.

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