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Staphylococcus aureus USA300-0114

ABSTRACT: RNA-seq of Wildtype Staphylococcus aureus USA300 NRS384

PROVIDER: PRJNA397207 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR5901540_1.fastq.gz	Fastqsanger.gz
	SRR5901540_2.fastq.gz	Fastqsanger.gz
	SRR5901541_1.fastq.gz	Fastqsanger.gz
	SRR5901541_2.fastq.gz	Fastqsanger.gz
	SRR5901542_1.fastq.gz	Fastqsanger.gz

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RNA-seq of Wildtype Staphylococcus aureus USA300 NRS384

Project description:Methicillin-resistant Staphylococcus aureus (MRSA) infections result in more than 200,000 hospitalizations and 10,000 deaths in the United States each year and remain an important medical challenge. To better understand the transcriptome of Staphylococcus aureus USA300 NRS384, a community-acquired MRSA strain, we have conducted an RNA-Seq experiment on WT samples.

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Expression analysis of Staphylococcus aureus USA300 LAC in response to vehicle and benzbromarone.

Project description:Compilation fo whole genome gene expression changes in Staphylococcus aureus USA300 LAC cultures grown in the presence of vehicle or the anti-gout drug benzbromarone. The drug was intially screened as effective against the agr quorum sensing system in Staphylococcus aureus AH1677. A microarray study using total RNA harvested from three cultures of Staphylococcus aureus USA300 LAC plus vehicle control and three cultures of Staphylococcus aureus USA300 LAC plus 12 uM benzbromarone.

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Project description:ArlRS is a two-component regulatory system in Staphylococcus aureus. Here we use RNA-sequencing to compare gene expression in a wild-type USA300 strain and an isogenic arlRS mutant.

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Project description:MgrA is a global regulator of gene expression in Staphylococcus aureus. Here we use RNA-sequencing to compare gene expression in a wild-type USA300 strain and an isogenic mgrA mutant.

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