Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA397731 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:DNA microarray analysis of Jmjd1a and/or Jmjd1b knockout embryonic stem cells
| PRJNA386154 | ENA
Project description:RNA-Seq analysis of Pold3 inducible-knockout embryonic stem cells
| PRJNA393469 | ENA
Project description:Transcriptome analysis of mouse embryonic stem cells upon PARP-1 knockout.
| PRJNA299024 | ENA
Project description:Expression data from Smad3 knockout embryonic stem cells and wild type embryonic stem cells
| PRJNA248668 | ENA
Project description:mouse embryonic fibroblasts, embryonic stem cells, and induced pluripotent stem cells were compared via metabolomic analysis
2018-08-02 | MSV000082680 | GNPS
Project description:Transcriptome analysis of histone demethylase Kdm2a knockout in mouse embryonic stem cells
| PRJNA1064250 | ENA
Project description:cDNA microarray analysis of mouse embryonic stem cells-derived hematopoietic progenitors compared to native hematopoietic stem cells
| PRJNA137581 | ENA
Project description:Introgressed variants from other species can be an important source of genetic variation because they may arise rapidly, can include multiple mutations on a single haplotype, and have often been pretested by selection in the species of origin. Although introgressed alleles are generally deleterious, several studies have reported introgression as the source of adaptive alleles-including the rodenticide-resistant variant of Vkorc1 that introgressed from Mus spretus into European populations of Mus musculus domesticus. Here, we conducted bidirectional genome scans to characterize introgressed regions into one wild population of M. spretus from Spain and three wild populations of M. m. domesticus from France, Germany, and Iran. Despite the fact that these species show considerable intrinsic postzygotic reproductive isolation, introgression was observed in all individuals, including in the M. musculus reference genome (GRCm38). Mus spretus individuals had a greater proportion of introgression compared with M. m. domesticus, and within M. m. domesticus, the proportion of introgression decreased with geographic distance from the area of sympatry. Introgression was observed on all autosomes for both species, but not on the X-chromosome in M. m. domesticus, consistent with known X-linked hybrid sterility and inviability genes that have been mapped to the M. spretus X-chromosome. Tract lengths were generally short with a few outliers of up to 2.7 Mb. Interestingly, the longest introgressed tracts were in olfactory receptor regions, and introgressed tracts were significantly enriched for olfactory receptor genes in both species, suggesting that introgression may be a source of functional novelty even between species with high barriers to gene flow.
| S-EPMC8784167 | biostudies-literature
Project description:Conditional knockout of Sox2 in embryonic and trophoblast stem cells.
| PRJNA143237 | ENA
Project description:Microarray analysis of satellite cells in Dnmt3a knockout mice
| PRJNA381442 | ENA