Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Chlamydia trachomatis strain:LGV L2 434/Bu

ABSTRACT: Chlamydia trachomatis L2 N-acetylated derivates of sulfamethoxazole resistant isolates Raw sequence reads

PROVIDER: PRJNA398542 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5942970.fastq.gz	Fastqsanger.gz
	SRR5942971.fastq.gz	Fastqsanger.gz
	SRR5942972.fastq.gz	Fastqsanger.gz
	SRR5942973.fastq.gz	Fastqsanger.gz
	SRR5942974.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 13

Similar Datasets

Chlamydia trachomatis L2/434/Bu

Project description:Chlamydia trachomatis L2/434/Bu Raw sequence reads

| PRJNA298309 | ENA

Chlamydia trachomatis L2/434/Bu

Project description:Chlamydia trachomatis L2/434/Bu Transcriptome or Gene expression

| PRJNA396761 | ENA

Chlamydia trachomatis L2/434/Bu(f)

Project description:Chlamydia trachomatis L2/434/Bu(f) Genome sequencing

| PRJNA182165 | ENA

Chlamydia trachomatis L2/434/Bu(i)

Project description:Chlamydia trachomatis L2/434/Bu(i) Genome sequencing

| PRJNA182150 | ENA

Chlamydia trachomatis strain:LGV-L2/434/Bu

Project description:Chlamydia trachomatis mutant strain genome sequencing

| PRJNA266635 | ENA

Chlamydia trachomatis L2/434/Bu

Project description:L2 serovar that caused lymphogranuloma vernerum

| PRJNA28583 | ENA

Chlamydia trachomatis L2/25667R

Project description:Chlamydia trachomatis L2/25667R genome sequencing

| PRJEA71105 | ENA

Transcriptomes of Chlamydia trachomatis L2 with Conditional GrgA deficiency

Project description:To determine the role that GrgA plays in chlamydial physiology, we constructed a Chlamydia trachomatis mutant that we term L/cgad-peig, in which the chromosomal grgA (ctl0766 or ct504) has been disrupted by Targetron mutagenesis, and the plasmid carries an inducible grgA under the control of anhydrotetracycline (ATC). RNA-Seq analysis was performed for L2/cgad-peig grown with and without ATC.

2023-11-29 | GSE234589 | GEO

Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu

Project description:In a forward genetic screen we identified a Chlamydia trachomatis L2/434/Bu mutant that causes rapid apoptotic and necrotic death of infected host cells. This phenotype could be linked to the loss of the inclusion membrane protein CpoS. We observed a reduction in cell death when infections were carried out in the presence of cycloheximide or actinomycin D, suggesting that the engagement of cell death depends on host transcription and protein synthesis. We applied RNA-Seq to study the transcriptional response of human endocervical epithelial (A2EN) cells to infection with wild-type or CpoS-deficient bacteria. At 6 hpi the transcriptional profiles of cells infected with the two strains were similar to each other and to the transcriptome of uninfected cells. However, by 18 hpi the transcriptional profile of cells infected with the mutant was strongly altered, with 400 host genes being upregulated greater than two-fold. Among those differentially expressed genes, we observed an enrichment of immunity-related genes, including in particular cytokine genes and interferon-stimulated genes. Overall these data demonstrate that the CpoS-deficient mutant induces an exacerbated interferon response.

2017-02-24 | GSE87110 | GEO

Chlamydia trachomatis RC-L2/55

Project description:Chlamydia trachomatis RC-L2/55 genome sequencing project.

| PRJNA66013 | ENA