Project description:In the present study, we investigated the effect of Lactococcus kimchii on healthspan using Caenorhabditis elegans as a model animal. The healthspan of the adult C. elegans fed the mixture of E. coli OP50 and Lactococcus kimchii was significantly longer than that of animals fed sole OP50 (control). Transcriptional profiling comparing Lactococcus kimchii- and control-fed animals suggested that genes related to insulin-like signaling pathway were upregulated by Lactococcus kimchii.