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MicroRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

ABSTRACT: microRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

PROVIDER: PRJNA415300 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6201890.fastq.gz	Fastqsanger.gz
	SRR6201900.fastq.gz	Fastqsanger.gz
	SRR6201891.fastq.gz	Fastqsanger.gz
	SRR6201901.fastq.gz	Fastqsanger.gz
	SRR6201892.fastq.gz	Fastqsanger.gz

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microRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

Project description:The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant microRNA (miRNA) expression may be involved in the pathogenesis and development of endometriosis. This study therefore aims to survey key miRNAs and further understand the mechanism of endometriosis. Paired expression profiling of miRNA in ectopic endometria compared with eutopic endometria were determined by high-throughput sequencing techniques in eight patients with ovarian endometriosis. Our study presents a unique insight into the regulatory network of this enigmatic disorder and possibly provides clues regarding replacement therapy of endometriosis.

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lncRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

Project description:The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant mRNA and lncRNA expressions may be involved in the pathogenesis and development of endometriosis. This study therefore aims to survey key TFs, genes and lncRNAs and further understand the mechanism of endometriosis. Paired expression profiling of mRNA and lncRNA in ectopic endometria compared with eutopic endometria were determined by high-throughput sequencing techniques in eight patients with ovarian endometriosis. Our study presents a unique insight into the regulatory network of this enigmatic disorder and possibly provides clues regarding replacement therapy of endometriosis.

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lncRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

Project description:lncRNA expression profilings in ectopic and eutopic endometria of ovarian endometriosis.

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Differential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis

Project description:Endometriosis is defined as the presence of endometrial tissue (eutopic tissue) outside the uterus (ectopic tissue). We assessed differentially expressed microRNAs in ectopic endometrium compared with eutopic endometrium. Comparison of paired eutopic/ectopic endometrium microRNAs from three patients.

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