Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Xenopus laevis

ABSTRACT: Xenopus laevis small RNA transcriptome after spinal cord injury

PROVIDER: PRJNA421211 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12334146.fastq.gz	Fastqsanger.gz
	SRR12334147.fastq.gz	Fastqsanger.gz
	SRR12334148.fastq.gz	Fastqsanger.gz
	SRR12334149.fastq.gz	Fastqsanger.gz
	SRR12334150.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Xenopus laevis

Project description:RNA-seq analysis after spinal cord injury in Xenopus laevis

| PRJDB9034 | ENA

Xenopus laevis laevis

Project description:Xenopus laevis laevis Transcriptome or Gene expression

| PRJNA247381 | ENA

Xenopus laevis

Project description:Xenopus laevis oocyte Transcriptome

| PRJNA714805 | ENA

Expression data from juvenile Xenopus laevis inner ear tissue

Project description:We implemented a functional genomics approach as a means to undertake a large-scale analysis of the Xenopus laevis inner ear transcriptome through microarray analysis. Microarray analysis uncovered genes within the X. laevis inner ear transcriptome associated with inner ear function and impairment in other organisms, thereby supporting the inclusion of Xenopus in cross-species genetic studies of the inner ear. Gene expression analysis of Xenopus laevis juvenile inner ear tissue. Inner ear RNA isolated from three groups of 5-10 juvenile X. laevis. Each biological replicate represents pooled inner ear RNA from 10-19 inner ears.

2012-05-04 | E-GEOD-37767 | biostudies-arrayexpress

Xenopus laevis

Project description:Xenopus laevis

| PRJNA269132 | ENA

Quantitative proteomics after spinal cord injury in a regenerative and a non-regenerative stage in Xenopus laevis

Project description:The capacity to regenerate the spinal cord after an injury is a coveted trait that only a limited group of non-mammalian organisms can achieve. In Xenopus laevis, this capacity is only present during larval or tadpole stages, but is absent during postmetamorphic frog stages. This provides an excellent model for comparative studies between a regenerative and a non-regenerative stage to identify the cellular and molecular mechanisms that explain the difference in regenerative potential. Here, we used iTRAQ chemistry to obtain a quantitative proteome of the spinal cord 1 day after a transection injury, and used sham operated animals as controls. We quantified a total of 6,384 proteins, with 172 showing significant differential expression in the regenerative stage and 240 in the non-regenerative stage, with an overlap of only 14 proteins. Functional enrichment analysis revealed that while the regenerative stage downregulated synapse/vesicle and mitochondrial proteins, the non-regenerative stage upregulated lipid metabolism proteins, and downregulated ribosomal and translation control proteins. Furthermore, STRING network analysis showed that proteins belonging to these groups are highly interconnected, providing interesting candidates for future functional studies.

2018-01-25 | PXD006993 | Pride

Xenopus laevis laevis

Project description:Xenopus laevis Transcriptome or Gene expression

| PRJNA255991 | ENA

Xenopus laevis

Project description:Xenopus laevis microRNA

| PRJNA325782 | ENA

Xenopus laevis

Project description:Xenopus laevis Transcriptome or Gene expression

| PRJNA336193 | ENA

Xenopus laevis

Project description:Xenopus laevis Transcriptome or Gene expression