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Homo sapiens

ABSTRACT: HITS-CLIP sequencing of RBM10 in HEK 293 Cells

PROVIDER: PRJNA422160 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6371005.fastq.gz	Fastqsanger.gz
	SRR6371006.fastq.gz	Fastqsanger.gz

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Project description:To determine the target genes of RBM10,we have employed microarray based gene expression profiling by knocking down RBM10 in HEK 293 cells. Microarray analysis after RBM10 knockdown on HEK 293 cells showed that over 1000 genes were down regulated while another 800 genes up regulated as a result of the knockdown. Among the down regulated genes, we found the significant presence of cardiovascular disease related genes, especially cardiac hypertrophy and heart failure.

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