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Suckling lamb perirenal fat transcriptome

ABSTRACT: Suckling lamb perirenal fat transcriptome

PROVIDER: PRJNA423080 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6392070_1.fastq.gz	Fastqsanger.gz
	SRR6392070_2.fastq.gz	Fastqsanger.gz
	SRR6392071_1.fastq.gz	Fastqsanger.gz
	SRR6392071_2.fastq.gz	Fastqsanger.gz
	SRR6392072_1.fastq.gz	Fastqsanger.gz

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Suckling lamb perirenal fat transcriptome

Project description:The aim of this study was to perform a comparative analysis of the perirenal fat transcriptomes of suckling lambs from two breeds with different growth and carcass characteristics. The perirenal fat tissue from 14 suckling lambs (Assaf= 8, Churra= 6) was used for the RNA-Seq analysis. The functional enrichment analysis of the 670 highly expressed genes (>150 fragments per kilobase of exon per million fragments mapped) in the perirenal fat transcriptome of both breeds revealed that the majority of these genes were involved in energy processes. The differential expression analysis performed identified 373 differentially expressed genes (DEGs) between the two compared breeds. In Assaf lambs, DEGs were enriched in Gene Ontology (GO) biological processes related to fatty-acid oxidation, while in Churra lambs, the majority of the significantly enriched GO terms were related to cholesterol synthesis, which suggests that upregulated DEGs in Assaf lambs are implicated in fat burning, while the Churra upregulated DEGs are linked to fat accumulation.

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