Project description:A novel gut-associated lysogenic phage, Bacteroides phage BV01, alters the host transcriptome and bile acid metabolism in Bacteroides vulgatus
Project description:IBD is characterized by chronic recurrences of intestinal inflammation and intestinal immune disturbances.Bacteroides vulgatus can alleviate DSS-induced colitis in mice, but the mechanism is unknown. The aim of this study was to examine the changes in gene expression in the intestinal tissue of mice with colitis following treatment with Bacteroides vulgatus by RNA sequencing.