Project description:Tinospora Cordifolia, an ayurvedic herbal compound, is studied to be an effective drug in Autoimmine disease. Several in vivo mouse model systems are reported to show its efficiency as a drug of therapeutic potential to treat autoimmune diseases. Th17 cells are the major T cells involved in the inflammatory responses in autoimmune diseases. The mechanistic insight into the therapeutic efficiency of Tinospora cordifolia is yet not studied. In this study we have tried to unravel the mechanism of action for the effect of water extract of Tinospora cordifolia on Th17 cells using genome wide expression approach.
