Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell RNA-Seq of E18.5 developing mouse kidney and human kidney organoids

ABSTRACT: Single cell RNA-Seq of E18.5 developing mouse kidney and human kidney organoids

PROVIDER: PRJNA428938 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6494010_1.fastq.gz	Fastqsanger.gz
	SRR6494010_2.fastq.gz	Fastqsanger.gz
	SRR6494020_1.fastq.gz	Fastqsanger.gz
	SRR6494020_2.fastq.gz	Fastqsanger.gz
	SRR6494030_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 50

Similar Datasets

Single cell RNA-Seq of E18.5 developing mouse kidney and human kidney organoids

Project description:These files represent single cell RNA-Seq data generated on a 10x Chromium genomics platform from three biological replicates from the embryonic day (E)18.5 developing mouse kidney and three biological replicates of iPSC-derived human kidney organoids differentiated according to our published protocol (Takasato et al., Nature Protocols 2016). When aggregated, the mouse data represents >6000 cells that passed our QC, containing most major cell types known to exist in the developing mouse kidney. The aggregated human organoid data contains of >7000 cells that passed our QC and contains populations representing endothelial cells, podocytes, stroma, nephron, and off-target populations with similarity to neurons.

2018-01-09 | GSE108291 | GEO

Single-cell analysis of human kidney organoids

Project description:Single-cell analysis of human kidney organoids

| PRJNA476702 | ENA

SINGLE CELL ANALYSIS OF POLYCYSTIC KIDNEY DISEASE USING HUMAN PLURIPOTENT STEM CELL- DERIVED KIDNEY ORGANOIDS

Project description:To reveal the key pathways involved in kidney cystogenesis. We performed single nuclei gene expression and ATAC profiling using kidney organoids from ARPKD patients-iPSCs derived organoids.

2023-10-09 | GSE244608 | GEO

Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations CL

Project description:Hepatocyte nuclear factor 1B (HNF1B) encodes a transcription factor expressed in developing human kidney epithelia. Heterozygous HNF1B mutations are the commonest monogenic cause of dysplastic kidney malformations (DKMs). To understand their pathobiology, we generated heterozygous HNF1B mutant kidney organoids from CRISPR-Cas9 gene-edited human ESCs and iPSCs reprogrammed from a family with HNF1B-asscociated DKMs. Mutant organoids contained enlarged malformed tubules and displayed deregulated cell turnover. This submission is RNAseq of organoids from MAN13 embryonic stem cells.

2024-04-29 | E-MTAB-12824 | biostudies-arrayexpress

Injured kidney organoids gene expression profile at single cell

Project description:Exploring single cell gene expression profile in kidney organoids modeling fibrosis

2022-01-01 | GSE164647 | GEO

Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations K

2024-04-29 | E-MTAB-12822 | biostudies-arrayexpress

Single-cell RNA-seq of engineered healthy human kidney organoids

Project description:Single-cell RNA-seq of engineered healthy human kidney organoids. These data are part of a larger investigation (data not provided here) showing that SARS-CoV-2 can directly infect engineered human blood vessel organoids and human kidney organoids which can be inhibited by human recombinant soluble ACE2 (hrsACE2), demonstrating that hrsACE2 can significantly block early stages of SARS-CoV-2 infections.

2020-04-05 | GSE147863 | GEO

Distalised kidney organoids

Project description:Distalised kidney organoids

| PRJNA765442 | ENA

Single-Cell Transcriptomics of Genome-Edited Kidney Organoids

Project description:Single-Cell Transcriptomics of Genome-Edited Kidney Organoids

| PRJNA559570 | ENA

Single-cell RNA-seq of human kidney organoids

Project description:Single-cell RNA-seq of human kidney organoids

| PRJNA750396 | ENA