Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from KP and KPY murine sarcoma tumors

ABSTRACT: Expression data from KP and KPY murine sarcoma tumors

PROVIDER: PRJNA432407 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Expression data from KP and KPY murine sarcoma tumors

Project description:YAP depletion in the KP tumor system results in smaller tumors and delayed tumor latency. We used microarrays to investigate changes in global gene expression due to YAP1 loss in KP tumors

2018-03-01 | GSE109920 | GEO

RNA-seq analysis between mouse UPS tumors (KP) and mouse UPS tumors without HIF-2alpha (KPH2)

Project description:Purpose: determine RNA expression differences in an unbiased fashion between UPS tumors derived from LSL-KrasG12D;Trp53-/- (KP) mice, and UPS tumors derived from LSL-KrasG12D;Trp53-/-;Epas1-/- (KPH2) mice. Epas1 encodes HIF-2alpha protein. RNA-seq was performed on KP (n = 4) and KPH2 (n = 4) derived UPS tumors using Illumina HiSeq 2000.

2015-12-31 | E-GEOD-67672 | biostudies-arrayexpress

Expression data from murine sarcoma cells treated with either DMSO or a combination of SAHA and JQ1 for 48 hours

Project description:SAHA/JQ1 reduces in vivo tumorigenesis and proliferation of KP sarcoma cells. This model recapitulates human undifferentiated pleomporphic sarcoma (UPS). We used microarrays to investigate changes in global gene expression in response to these drugs.

2018-03-01 | GSE109923 | GEO

RNAseq to compare chemokine expression profiles in KP line vs total KP lung tumors tissues

Project description:To investigate the chemokines expressed by the KP cancer line and to compare it to chemokines expressed in lung tissues upon inoculation of KP tumor cells

2022-04-07 | GSE200126 | GEO

RNA-seq analysis between mouse UPS tumors (KP) and mouse UPS tumors without HIF-2alpha (KPH2)

2015-12-31 | GSE67672 | GEO

RNAseq to compare chemokine expression profiles in KP line vs total KP lung tumors tissues

Project description:RNAseq to compare chemokine expression profiles in KP line vs total KP lung tumors tissues

| PRJNA823023 | ENA

Expression data from Sarcoma Tumors expressing the EWSR1-CREB fusions

Project description:Expression data from Sarcoma Tumors expressing the EWSR1-CREB fusions

| PRJNA708292 | ENA

Exome sequencing of KP and KPM lung tumors.

Project description:Exome sequencing of KP and KPM lung tumors.

| PRJNA715567 | ENA

Expression data from Sarcoma Tumors expressing the EWSR1-CREB fusions [microarray]

Project description:Expression data from Sarcoma Tumors expressing the EWSR1-CREB fusions [microarray]

| PRJNA708295 | ENA

Expression data of mouse Ewing's sarcoma

Project description:Ewing’s sarcoma is highly malignant bone tumor that involves childhood and adolescent, and its nature has not been well understood. To clarify its cellular origin and the mechanisms of tumorigenesis, we used ex vivo approach to create a murine model for Ewing’s sarcoma. The osteochondrogenic progenitors derived from the facial zone (FZ) of murine long bones at late gestation were purified by microdissection, introduced with EWS-FLI1 or EWS-ERG retroviruses and transplanted into nude mice. Ewing’s sarcoma-like small round cell sarcoma developed at 100% penetrance, whereas tumor induction was less effective when growth place (GP)-derived cells were used. The different response of gene expression to EWS-FLI1 between FZ and GP cells suggests importance of the specific cellular context for EWS-FLI1 to induce Ewing’s sarcoma. The Wnt/β-catenin pathway was involved in close relationship to the cellular context, with Dkk2 and Wipf1 as important downstream modulators. Furthermore, gene expression profiling revealed similarity between our models and human Ewing’s sarcoma. These results indicate that Ewing’s sarcoma originates from the embryonic osteochondrogenic progenitor.

2014-06-30 | GSE32615 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data