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Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716 [400K]

ABSTRACT: Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716 [400K]

PROVIDER: PRJNA432777 | ENA |

REPOSITORIES: ENA

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Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716 [400K]

Project description:Double minutes (DMs), a major form of gene amplification, commonly carry oncogenes or chemoresistance-related genes that are associated with the occurrence, development and prognosis of tumors. Thus, probing molecular structures of DMs allows us to further understand molecular mechanisms underlying tumorigenesis. In this study, we identified four amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716. These amplification regions localized in two populations of DMs. Through a combined analysis on the results of array CGH, high throughput sequencing, multiplex-fluorescence in situ hybridization and chromosome walking results, we constructed molecular structures of the two populations of DMs at nucleotide resolution.

2018-12-31 | GSE110069 | GEO

Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716 [custom 180K]

2018-12-31 | GSE110070 | GEO

Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716

Project description:Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716

| PRJNA432704 | ENA

Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716 [custom 180K]

Project description:Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716 [custom 180K]

| PRJNA432774 | ENA

Over-expression of YAP1 in NCI-H716 colorectal cancer cells

Project description:YAP1 plays importance roles in development of colorectal cancer as evidenced by their overexpression in colorectal cancer and their expression promoted cell proliferation and survival of colorectal cancer cells. In order to understand potential roles of YAP1 in colorectal cancer, we over-expressed constitutively active YAP1 mutant in NCI-H716 colorectal cancer cells and identified and analyzed genes whose expression is activated by YAP1 activation in colorectal cancer. Pre-clinical study

2015-02-04 | E-GEOD-50490 | biostudies-arrayexpress

Over-expression of YAP1 in NCI-H716 colorectal cancer cells

2015-02-04 | GSE50490 | GEO

Identified amplification regions by high-density array CGH in a human colorectal adenocarcinoma cell line NCI-H716

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-12-31 | GSE110071 | GEO

Comparative gene expression in NCI-H716 cells grown in different glucose concentrations

Project description:We performed RNA-Seq whole transcriptome analysis of H716 cells grown in two glucose concentrations.

2019-08-27 | GSE136369 | GEO

NCI-H716 cell line treated with Akkermansia muciniphila secerted protein P9

Project description:NCI-H716 cell line treated with Akkermansia muciniphila secerted protein P9

| PRJEB36198 | ENA