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Expression data from 13 patients with colorectal cancer

ABSTRACT: Expression data from 13 patients with colorectal cancer

PROVIDER: PRJNA433208 | ENA |

REPOSITORIES: ENA

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Expression data from 13 patients with colorectal cancer

Project description:Colorectal cancer is a highly heterogeneous disease, with variable molecular pathogenesis, involving multiple genomic and epigenetic alterations. Despite the significant advances in the diagnosis and treatment of colorectal cancer, it remains a major cause of morbidity and mortality, especially for countries in Northern America and Europe, as also in New Zealand & Australia. In this direction, the introduction of gene expression signatures derived from multiple layers of molecular & clinical dissection, may resolve the problems of heterogeneity and improve robust disease stratification. We used microarrays to monitor the global gene expression alterations of primary adenocarcinomas and matched normal samples from each patient, to unravel the critical biological processes that are involved in CRC progression.

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