Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

P53 ChIP-seq in PHA-stimulated human T-lymphocytes

ABSTRACT: p53 ChIP-seq in PHA-stimulated human T-lymphocytes

PROVIDER: PRJNA433546 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6691990.fastq.gz	Fastqsanger.gz
	SRR6692000.fastq.gz	Fastqsanger.gz
	SRR6691991.fastq.gz	Fastqsanger.gz
	SRR6692001.fastq.gz	Fastqsanger.gz
	SRR6691992.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

p53 ChIP-seq in PHA-stimulated human T-lymphocytes

Project description:ChIP-seq profiles of p53 binding in PHA-stimulated human T-lymphocytes treated with either Doxorubicin, Nutlin-3, or DMSO

2018-07-24 | GSE110368 | GEO

Gene expression analysis of the p53 response in PHA-stimulated human T-lymphocytes

Project description:Gene expression analysis of the p53 response in PHA-stimulated human T-lymphocytes treated ex vivo with either Doxorubicin, Nutlin-3, or DMSO

2018-07-24 | GSE110369 | GEO

Gene expression analysis and p53 ChIP-seq in PHA-stimulated human T-lymphocytes

Project description:Gene expression analysis and p53 ChIP-seq in PHA-stimulated human T-lymphocytes

| PRJNA433542 | ENA

Gene expression analysis of the p53 response in PHA-stimulated human T-lymphocytes

Project description:Gene expression analysis of the p53 response in PHA-stimulated human T-lymphocytes

| PRJNA433547 | ENA

Gene expression analysis and p53 ChIP-seq in PHA-stimulated human T-lymphocytes

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-07-24 | GSE110370 | GEO

CDK inhibitors PHA-848125 and PHA-690509 profiling on A2780

Project description:The effects of the CDK inhibitors PHA-848125 and PHA-690509 on the A2780 cell line were analysed by gene expression profiling.

2010-07-14 | GSE18486 | GEO

PHA-4 organogenesis

Project description:The pha-4 locus encodes a forkhead box A (FoxA/HNF3) transcription factor homolog that specifies organ identity for Caenorhabditis elegans pharyngeal cells. We used microarrays to identify pharyngeal genes and analyzed those genes to determine which were direct PHA-4 targets. Our data suggest that PHA-4 directly activates most or all pharyngeal genes. Furthermore, the relative affinity of PHA-4 for different TRTTKRY (R = A/G, K = T/G, Y = T/C) elements modulates the onset of gene expression, providing a mechanism to activate pharyngeal genes at different developmental stages. We suggest that direct transcriptional regulation of entire gene networks may be a common feature of organ identity genes. A genotyping experiment design type classifies an individual or group of individuals on the basis of alleles, haplotypes, SNP's. Keywords: genotyping_design

2005-11-26 | GSE3681 | GEO

Discovery of the p53 targetome in MCF7 cells from ChIP-Seq data

Project description:RNA-seq and ChIP-seq on MCF-7 breast cancer cell line upon activation of p53 by the non-genotoxic small molecule Nutlin-3a ChIP-seq on p53 in MCF7 with Nutlin-3a stimulation (S) in triplicate, and the control (input), in stimulated and non stimulated, using illumina HiSeq 2000

2014-05-27 | E-GEOD-47041 | biostudies-arrayexpress

CDK inhibitors PHA-848125 and PHA-690509 profiling on A2780

Project description:The effects of the CDK inhibitors PHA-848125 and PHA-690509 on the A2780 cell line were analysed by gene expression profiling. The A2780 cell line was treated with PHA-848125 (CDk-125) or PHA-690509 (CDk-509) for 6 hours at a dose equal to 5 times the IC50. Untreated A2780 cells were used as a control. Three replicates per treatment.

2010-07-14 | E-GEOD-18486 | biostudies-arrayexpress

Cross-linking Analysis (HSP70-HSP90-CHIP)

Project description:Some molecular chaperones are involved not only in assisting the folding of proteins but also, given appropriate conditions, in their degradation. This is the case of Hsp70 and Hsp90, which in concert with the cochaperone CHIP –an E3 ligase–, direct their bound substrate to degradation through ubiquitination. We have generated complexes between the chaperone (Hsp70 or Hsp90), the cochaperone CHIP and, as substrate, a p53 variant containing the GST protein (p53-TMGST). The two ternary complexes (Hsp70:p53-TMGST:CHIP and Hsp90:p53-TMGST:CHIP) ubiquitinate the substrate, and this is done with a higher efficiency than in the absence of the chaperones. The 3D structures of the two complexes, obtained using a combination of cryoelectron microscopy and crosslinking mass spectrometry, show the substrate located between the chaperone and the cochaperone, which suggests an ubiquitination mechanism. Both complexes are extremely flexible, which is crucial for the ubiquitination process.

2019-03-06 | PXD009777 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data