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Streptococcus agalactiae CNCTC 10/84

ABSTRACT: Streptococcus agalactiae Transcriptome WT vs brpA mutant

PROVIDER: PRJNA435418 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR7010515_1.fastq.gz	Fastqsanger.gz
	SRR7010515_2.fastq.gz	Fastqsanger.gz
	SRR7010516_1.fastq.gz	Fastqsanger.gz
	SRR7010516_2.fastq.gz	Fastqsanger.gz
	SRR7010517_1.fastq.gz	Fastqsanger.gz

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Streptococcus agalactiae CNCTC 10/84

Project description:Streptococcus agaiactiae CNCTC 10/84 Genome sequencing

| PRJNA229124 | ENA

Complete Genome Sequence of Streptococcus agalactiae CNCTC 10/84, a Hypervirulent Sequence Type 26 Strain.

Project description:Streptococcus agalactiae (group B Streptococcus [GBS]) is a human pathogen with a propensity to cause neonatal infections. We report the complete genome sequence of GBS strain CNCTC 10/84, a hypervirulent clinical isolate frequently used to study GBS pathogenesis. Comparative analysis of this sequence may shed light on novel pathogenic mechanisms.

| S-EPMC4276828 | biostudies-literature

Genome-wide transcriptomic data from Streptococcus agalactiae strain CNCTC 10/84 wild type and an allelic exchange isogenic mutant lacking the GntR-class putative transcription factor mrvR

Project description:As part of a broader study to identify genes that contribute to fitness of the human pathobiont Streptococcus agalacitae (group B Streptococcus), we identified a GntR-class transcription factor, named mrvR, which contributes to bacterial persistence in human amniotic fluid and multipe virulence phenotypes. In order to understand the transcriptome of mrvR, whole-genome transcriptomic analysis was performed with wild type group B Streptococcus and an mrvR deletion mutant at three growth phases.

2021-02-03 | GSE165992 | GEO

Streptococcus agalactiae stringent response RNA-seq

Project description:Transcriptome analysis of Streptococcus agalactiae (group B Streptococcus) grown under control conditions or coincubated with serine hydroxamate to induce the bacterial stringent response

2017-11-14 | GSE98398 | GEO

CiaR Transcriptome in Streptococcus agalactiae

Project description:Regulation of gene expression in response to variable and often adverse environmental conditions is an essential component of microbial pathogenesis. We identified the two-component regulatory system CiaRH in a screen for genes essential for the survival of Streptococcus agalactiae (Group B Streptococcus, GBS) on exposure to in vitro models of environmental stress. We constructed site-directed, non-polar deletion mutations in the regulator gene ciaR and compared the growth of CiaR mutant GBS to wild-type GBS under stressed conditions. CiaR mutant GBS are more sensitive than wild-type GBS to elevated temperature, low pH, chemical mutagens and ultraviolet light; the mutants are also more sensitive to cell-wall active antibiotics and antimicrobial peptides. CiaR mutant strains are markedly attenuated in a mouse model of GBS sepsis. To determine the genes regulated by CiaR that account for these defects, transcriptional profiling was performed using DNA microarray analysis, comparing wild-type GBS to CiaR mutant GBS under non-stressed conditions.

2012-11-18 | GSE14569 | GEO

Streptococcus agalactiae temperature changes

Project description:Streptococcus agalactiae (Lancefield’s group B Streptococcus, GBS) is a major bacterial species of genus Streptococcus and has medical and veterinary importance by affecting mainly humans (Maione et al., 2005; Johri et al., 2006), cattle (Keefe, 1997) and fish (Mian et al., 2009). The GBS is the most important pathogen for the Nile tilapia, a global commodity of the aquaculture sector, causing outbreaks of septicemia and meningoencephalitis (Hernández et al., 2009; Mian et al., 2009).

2018-11-23 | PXD009330 | Pride

RNA sequencing analysis of SczA-deficient Streptococcus agalactiae

Project description:Total RNA was isolated from mid-log phase Streptococcus agalactiae cells deficient in SczA (∆sczA strain GU2791), grown in Todd-Hewitt broth (THB) medium and sequenced using Illumina NextSeq500.

2021-06-01 | GSE167901 | GEO

RNA sequencing analysis of covR-deficient Streptococcus agalactiae

Project description:Total RNA was isolated from mid-log phase Streptococcus agalactiae cells deficient in CovR (∆covR strain GU2400), grown in Todd-Hewitt broth (THB) medium and sequenced using Illumina NextSeq500

2021-06-01 | GSE167898 | GEO

RNA sequencing analysis of CopY-deficient Streptococcus agalactiae

Project description:Total RNA was isolated from mid-log phase Streptococcus agalactiae cells deficient in CopY (∆copY strain GU2857), grown in Todd-Hewitt broth (THB) medium and sequenced using Illumina NextSeq500.

2021-06-01 | GSE167896 | GEO

RNA sequencing analysis of Streptococcus agalactiae 874391 (wild-type)

Project description:Total RNA was isolated from mid-log phase Streptococcus agalactiae 874391 wild-type cells grown in Todd-Hewitt broth (THB) medium and sequenced using Illumina NextSeq500

2021-05-11 | GSE167894 | GEO

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