Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Study of sarcopenia in human muscle biopsies of elderly individuals

ABSTRACT: Study of sarcopenia in human muscle biopsies of elderly individuals

PROVIDER: PRJNA435589 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6761970_1.fastq.gz	Fastqsanger.gz
	SRR6761970_2.fastq.gz	Fastqsanger.gz
	SRR6761980_1.fastq.gz	Fastqsanger.gz
	SRR6761980_2.fastq.gz	Fastqsanger.gz
	SRR6761990_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 1904

Similar Datasets

Study of sarcopenia in human muscle biopsies of elderly individuals, Hertfordshire Sarcopenia Study

2019-11-14 | GSE111006 | GEO

Study of sarcopenia in human muscle biopsies of elderly individuals, Jamaica Sarcopenia Study

Project description:Purpose: The main goal of this study is to compare skeletal muscle transcriptome profilings derived from muscle impaired versus healthy subjects. Methods: We use high coverage RNA sequencing of human skeletal muscle biopsies to analyze genome-wide transcriptional changes in human sarcopenia benchmarked to healthy elderly controls.

2019-11-14 | GSE111010 | GEO

Study of sarcopenia in human muscle biopsies of elderly individuals, Jamaica Sarcopenia Study

Project description:Study of sarcopenia in human muscle biopsies of elderly individuals, Jamaica Sarcopenia Study

| PRJNA435583 | ENA

Study of sarcopenia in human muscle biopsies of elderly individuals, Hertfordshire Sarcopenia Study

Project description:Study of sarcopenia in human muscle biopsies of elderly individuals, Hertfordshire Sarcopenia Study

| PRJNA435580 | ENA

Study of sarcopenia in human muscle biopsies of elderly individuals, Singapore Sarcopenia Study

Project description:Study of sarcopenia in human muscle biopsies of elderly individuals, Singapore Sarcopenia Study

| PRJNA435592 | ENA

Study of sarcopenia in human muscle biopsies of elderly individuals, Singapore Sarcopenia Study

Project description:Purpose: The main goal of this study is to compare skeletal muscle transcriptome profilings derived from sarcopenic versus healthy subjects. Methods: We use high coverage RNA sequencing of human skeletal muscle biopsies to analyze genome-wide transcriptional changes in human sarcopenia benchmarked to healthy elderly controls. Results: Muscle transcriptomic profiles demonstrate a prominent signature of mitochondrial dysfunction in sarcopenic patients. Conclusions: Our study supports the fundamental role of mitochondrial dysfunction in driving pathological muscle and mobility decline in the elderly.

2019-11-14 | GSE111016 | GEO

Study of sarcopenia in human muscle biopsies of elderly individuals

Project description:This SuperSeries is composed of the SubSeries listed below.

2019-11-14 | GSE111017 | GEO

Epigenome analysis of muscle tissue samples from male participants of the Hertfordshire Sarcopenia Study (HSS) and Hertfordshire Sarcopenia Study extension (HSSe)

Project description:Genome wide DNA methylation profiling of muscle tissue genomic DNA. The Illumina Infinium MethylationEPIC array was used to obtain DNA methylation profiles across approximately 850,000 CpGs. Samples were male, taken from both the Hertfordshire Sarcopenia Study (HSS, n=34) and the Hertfordshire Sarcoepnia Study exension (HSSe, n=44), to determine DNA methylation associations with measures of muscle mass and function. We further aimed to test whether differences in the muscle methylome are associated with sarcopenia in older individuals. We found significant associations between DNA methylation in the muscle tissue and sarcopenia, as well as individual measures of muscle mass and function, enriched around EZH2 binding sites.

2021-12-15 | GSE154980 | GEO

Profiling muscle from aged rat model for sarcopenia

Project description:This program aims at identifying a muscle gene signature associated with aging in rat sarcopenia model The profiling data was analyzed by identifying genes that were up- and down-regulated at selected p value and fold change in the muscle of aged rats compared to the young controls.

2013-03-22 | E-GEOD-38077 | biostudies-arrayexpress