Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene chip analysis of NPCs with and without cocultured with ASCs

ABSTRACT: Gene chip analysis of NPCs with and without cocultured with ASCs

PROVIDER: PRJNA445282 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Gene chip analysis of ASCs with and without cocultured with NPCs

Project description:Gene chip analysis of ASCs with and without cocultured with NPCs

| PRJNA487348 | ENA

Gene chip analysis of NPCs with and without cocultured with ASCs

Project description:We used microarrays to detail the global programme of gene expression underlying the coculturing of degenerate NPCs and ASCs and identified distinct classes of altered genes and ncRNAs during this process.

2018-03-23 | GSE112216 | GEO

Gene chip analysis of ASCs with and without cocultured with NPCs

Project description:We used microarrays to detail the global programme of gene expression underlying the coculturing of ASCs and degenerative NPCs and identified distinct classes of altered genes and ncRNAs during this process.

2019-08-31 | GSE118927 | GEO

Comparison of WAT EPCs vs WAT ASCs

Project description:Human adipose tissue contains two populations of progenitors (EPCs and ASCs) with cooperative roles in breast cancer. EPCs (CD45-CD34+CD31+CD13-CCRL2+) can generate endothelial cells. ASCs (CD45-CD34+CD31-CD13+CD140b+) are mesenchymal progenitors which generated pericytes. CD13+ cells and CD13- cells from 7 Lipotransfer aspirate

2013-07-05 | E-GEOD-44302 | biostudies-arrayexpress

ChIP-Seq of Sox2 and Brn2 in ESCs, NPCs, and differentiating ESCs

Project description:We analyzed the genome-wide binding of Sox2 and POU factor partner factors, Oct4 in ESCs (using published datasets PMID:18692474 and GSM307137, GSM307154, GSM307155) and Brn2 in NPCs. We found that Sox2 and Oct4 co-occupied a large subset of promoters and enhancers in ESCs, but that Sox2 and Brn2 co-occupy predominantly enhancers. Further, we overexpressed Brn2 in differentiating ESCs and showed that ectopic Brn2 recruited Sox2 to NPC-specific targets, resulting in skewed differentiation towards the neural lineage. Examination of transcription factor binding in ESCs, NPCs, and differentiating ESCs by ChIP-Seq.

2013-02-20 | E-GEOD-35496 | biostudies-arrayexpress

RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d)

Project description:We indirectly cocultured OVCAR5-RFP cells using a 0.45 micron Boyden chamber with or without adipocytes for 4 days, collected the RNA from adipocytes, and performed RNA-seq

2018-03-08 | GSE111538 | GEO

Comparison of WAT EPCs vs WAT ASCs

2013-07-05 | GSE44302 | GEO

Microarray for density study of mouse Adipose-derived Stromal Cells (ASCs)

Project description:Cytoskeletal tension is an intracellular mechanism through which cells convert a mechanical signal into a biochemical response, including production of cytokines and activation of various signaling pathways. Adipose-derived stromal cells (ASCs) were allowed to spread into large cells by seeding them at a low-density (1,250 cells/cm2), which was observed to induce osteogenesis. Conversely, ASCs seeded at a high-density (25,000 cells/cm2) featured small cells that promoted adipogenesis. RhoA and actin filaments were altered by changes in cell size. Blocking actin polymerization by Cytochalasin D influenced cytoskeletal tension and differentiation of ASCs. To understand the potential regulatory mechanisms leading to actin cytoskeletal tension, cDNA microarray was performed on large and small ASCs. Connective tissue growth factor (CTGF) was identified as a major regulator of osteogenesis associated with RhoA mediated cytoskeletal tension. Subsequently, knock-down of CTGF by siRNA in ASCs inhibited this osteogenesis. Therefore, we conclude that cytoskeletal tension is important for CTGF-regulated ASC osteogenic differentiation. Computed

2011-01-16 | E-GEOD-19924 | biostudies-arrayexpress

Cancer cells cocultured with macrophage

Project description:Cancer cells cocultured with macrophage

| PRJNA877107 | ENA

Microarray for density study of mouse Adipose-derived Stromal Cells (ASCs)

2011-01-16 | GSE19924 | GEO