Project description:To compare the irradiated KG1a data with other irradiated cells/cell lines for finding out the similarity and differences with respect to various gene ontologies

2016-12-31 | GSE73486 | GEO

LiCl treated KG1a cells, irradiated at 4Gy and 8Gy, incubated for 48hr

Project description:Gene expression following ionizing radiation exposure to LiCl treated cells

2018-07-02 | GSE102129 | GEO

Wildtype (N2) C. elegans: Control vs. 10mM LiCl treated for 48hr at 25oC

Project description:Transcriptional profiling of adult C. elegans comparing control untreated with populations exposed to 10mM LiCl. Populations treated from larval stage L4 for 48hr at 25oC. 10mM LiCl contained in the Nematode Growth Media (NGM) Keywords: Drug treatment

2007-12-01 | GSE8058 | GEO

Human glioma cell line T98G: BAP-PCBP2 RIP vs. BAP-GFP RIP (Control)

Project description:RIP-Chip analysis of PCBP2 and identification of preferentially associated mRNAs. T98G cells were transfected transiently with BAP-tagged constructs. BAP-tagged proteins were biotinylated in vivo by the co-transfected hBirA enzyme. RNPs were recovered via precipitation with Steptavidin-sepharose beads. Finally, RNAs were purified and analyzed on microarrays. BAP-GFP as control was used in three independent sets of experiments.

2013-07-24 | GSE44048 | GEO

Expression data from human OC+BAP+ double positive versus OC-BAP- double negative cells

Project description:Subpopulation of circulating monocyte/macrophage lineage cells show a calcifying ability in vivo and in vitro. These cells may contribute to intimal calcification within atherosclerotic lesions and may have pathophysiological clinical and therapeutic implication in vascular disorders. Such cells express Osteocalcin (OC) and Bone Alkaline Phosphatase (BAP). We analysed the expression profile of human OC+BAP+ cells versus OC-BAP- cells

2013-05-17 | GSE47060 | GEO

Transcription profiling of mouse Bax null versus NGF-Bax double null animals

Project description:We report that developmental competition between sympathetic neurons for survival is critically dependent on a sensitization process initiated by target innervation and mediated by a series of feedback loops. Target-derived nerve growth factor (NGF) promoted expression of its receptor TrkA in neurons and prolonged TrkA-mediated signals. NGF also controlled expression of brain derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4), which, through the receptor p75, can kill neighboring neurons with low retrograde NGFâ??TrkA signaling whereas neurons with high NGFâ??TrkA signaling are protected. Perturbation of any of these feedback loops disrupts the dynamics of competition. We suggest that three target-initiated events are essential for rapid and robust competition between neurons: sensitization, paracrine apoptotic signaling, and protection from such effects. Experiment Overall Design: This experiment examine gene expression differences in superior cervical ganglia fro P0 bax null versus NGF-Bax double null animals. The Bax genotype was used in order to prevent the neuronal cell death normally observed in the NGF null animal.

2008-06-11 | E-GEOD-10498 | biostudies-arrayexpress

Human glioma cell line T98G: BAP-PCBP2 RIP vs. BAP-GFP RIP (Control)

2013-07-24 | E-GEOD-44048 | biostudies-arrayexpress