Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Widespread and Functional RNA Circularization in Localized Prostate Cancer.

ABSTRACT: Widespread and Functional RNA Circularization in Localized Prostate Cancer.

PROVIDER: PRJNA450081 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6999010_1.fastq.gz	Fastqsanger.gz
	SRR6999010_2.fastq.gz	Fastqsanger.gz
	SRR6999020_1.fastq.gz	Fastqsanger.gz
	SRR6999020_2.fastq.gz	Fastqsanger.gz
	SRR6999001_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 132

Similar Datasets

Widespread and Functional RNA Circularization in Localized Prostate Cancer.

Project description:This SuperSeries is composed of the SubSeries listed below.

2019-02-07 | GSE113124 | GEO

Multiregion Sequencing of Localized Prostate Cancer

Project description:Multiregion Sequencing of Localized Prostate Cancer

| PRJNA530801 | ENA

Multiregion Sequencing of Localized Prostate Cancer

Project description:Multiregion Sequencing of Localized Prostate Cancer

| PRJNA412429 | ENA

Epigenomic alterations in localized and advanced prostate cancer

Project description:Here we used Illumina NGS for high-throughput profiling of the DNA methylome in seven human benign prostate tissues, seven human primary prostate cancer and six human castration resistant prostate cancer patient samples. These data were used to profile the CpG cytosine methylation pattern at single base resolution in each sample and to determine differentially methylated cytosines and regions among samples. Enhanced Reduced Representation Bisulfite Sequencing (ERRBS, MspI,150M-bM-^@M-^S400 bp size fractions) of 20 human prostate tissues (benign prostate tissues, localized and metastatic prostate cancer)

2013-07-03 | E-GEOD-41701 | biostudies-arrayexpress

Whole Exome Sequencing of Localized Prostate Cancer Patients

Project description:We performed whole-exome sequencing on localized prostate cancer patients to validate tumor content as part of a single-cell RNA sequencing study of localized prostate cancer patients.

| EGAS00001005685 | EGA

Genomic hallmarks of localized, non-indolent prostate cancer

Project description:Genomic hallmarks of localized, non-indolent prostate cancer

| PRJNA327861 | ENA

Overexpression and knockdown experiment for circCSNK1G3

Project description:Standard RNA analyses using microarrays and low-coverage polyadenylation enriched RNA-Sequencing (RNA-Seq) cannot fully characterize the complexity of the cancer transcriptome. To fully elucidate the transcriptome of prostate tumours, we performed ultra-deep total RNA-Seq on 144 localized prostate tumours with long-term clinical follow up. Analysis of linear RNAs identified a transcriptomic subtype associated with the aggressive intraductal carcinoma subhistology, and a fusion gene profile that differentiates localized from metastatic prostate cancers. Analysis of back-splicing events identified widespread RNA circularization, with the average tumour expressing 7,140 distinct circular RNAs. The degree of aberrant circRNA production is correlated to disease progression in multiple clinical cohorts. Loss of function screens identified 11.3% of the screened circRNAs as essential to prostate cancer proliferation, and for 93.6% of these, their parental linear genes are not required for proliferation. Follow-up studies on circCSNK1G3 revealed its role in regulating cell cycle progression. Ultra-deep transcriptome sequencing thus provides a more comprehensive view of the linear and circular transcriptional and functional landscapes of localized prostate cancer.

2019-02-07 | GSE113121 | GEO

RNA-Seq with and without RNase treatment in PCa cell lines

2019-02-07 | GSE113120 | GEO

Loss of function shRNA screen on circRNA and linear genes in PCa cell lines

2019-02-07 | GSE113119 | GEO

Expression profile of localized primary prostate cancer samples and the matched normal tissues

Project description:To identify new oncogenic drivers in prostate cancer, we performed transcriptome analysis of localized primary prostate cancer samples and the matched normal tissues.

2021-05-01 | GSE114740 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data